What Are The Medical Benefits of Marijuana? - Part 3.

Photo Credits: Leaf Science

Photo Credits: Leaf Science

In the last post, we continued to look at the conditions where medical marijuana is effective. It’s not done yet! We’ll continue the discussion below.

While the relationship between marijuana and heart disease is complicated, and cannabis can actually exacerbate symptoms in some users by increasing heart rate and blood pressure, scientists have found low doses of THC can reduce damage from heart attacks, and CBD can be used as a treatment for cardiovascular disease. Cannabis may also reduce the severity and lessen the impact of a stroke. Although most studies thus far have been animal studies, researchers believe medical cannabis may help treat the symptoms of Huntington’s disease, and one human study found synthetic THC improved motor-related symptoms of the disorder. Animal studies have found cannabis may slow the progression of Amyotrophic lateral sclerosis, and many properties of cannabis could help reduce pain, relax muscles, reduce saliva, stimulate appetite, and induce sleep. Synthetic cannabinoids also improved pain symptoms in fibromyalgia patients, and one survey found patients actually preferred cannabis to any approved pharmaceutical medication.

New support is starting to accumulate for the use of marijuana for Alzheimer’s disease. Marijuana may be able to do so by reducing inflammation and the formation of plaques. Marijuana has been found to alleviate tics and be well tolerated in patients with Tourette’s syndrome. Cannabis topicals are now offered as effective treatments for varying skin disorders, and its anti-inflammatory and anti-itching properties make it effective for the treatment of acne, dermatitis, and psoriasis. Marijuana may also help those who suffer from sleep disorders like insomnia and sleep apnea fall asleep quicker and improve breathing during sleep. Lastly, and probably most well known, is medical marijuana’s ability to treat epilepsy. Specifically, the cannabinoid CBD is well-tolerated and effective in reducing the frequency and severity of seizures.

There are even many more conditions to talk about regarding medical marijuana treatment. Keep reading as we conclude our discussion in the next post! This information has been provided by Leaf Science and approved by our Chief Medical Officer.

Research Finds Cannabinoids May Help Treat Certain Skin Diseases

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

A new research review conducted by researchers at the University of Colorado Anschutz Medical Campus suggests the anti-inflammatory properties found in cannabinoids may be able to soothe skin conditions like psoriasis, eczema, atopic and contact dermatitis, and even melanomas. Headed by Dr. Robert Dellavalle, MD, researchers looked at literature surrounding cannabinoids and skin conditions. In one study, cannabinoids that were injected into skin tumors in mice prevented the growth of the tumors. Another study found THC reduced swelling and inflammation in mice. In yet another study, 8/21 patients who used cannabinoids topically twice a day over the course of three weeks witnessed symptoms of itching eliminated. Through topical applications, active compounds penetrate and are absorbed through the skin, where they can interact with nearby cells' receptors without providing any psychotropic effects. 

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. 

What is CBG (Cannabigerol)?

Photo Credit: Leaf Science

Photo Credit: Leaf Science

When learning about medical marijuana, it's easy to find information surrounding the major cannabinoid compounds like CBD and THC, but there are some lesser known cannabinoids that are also valuable. One non-psychoactive cannabinoid, cannabigerol (CBG), is considered the building block or parent of THC and CBD, and once it is synthesized, it is converted into these other cannabinoids. Most cannabis strains have little to no concentrations of CBG, and it may be more common in hemp. 

The cannabinoid can buffer against the psychoactive effects of other cannabinoids by promoting synergy. It also acts on both CB1 and CB2 receptors, although its interactions are weak in comparison with stronger cannabinoids like THC. Still, it may benefit in the treatment of central nervous system disorders, neurological diseases, skin disorders, chronic pain, and more. It may also combat depression by blocking serotonin receptors. CBG increases anandamide levels, and thereby benefits the regulation of sleep, appetite, and memory. CBG inhibits the uptake of the brain chemical GABA, which regulates the activity of neurons, and it may do so at a greater extent than both THC and CBD. More research is left to be desired, but studies have already shown CBG may stimulate bone formation and healing, halt tumor growth, act as an antifungal and antibacterial agent, relieve pain, provide neuroprotective effects, reduce inflammation, and treat overactive bladder, psoriasis or other skin disorders, glaucoma, depression, and anxiety. 

This information has been provided by Leaf Science and approved by our Chief Medical Officer. 

What Can't It Do? Study Suggests Cannabis Could Help Treat Various Skin Diseases

Photo Credit: Civilized 

Photo Credit: Civilized 

A report published in in the Journal of the American Academy of Dermatology suggests  topical creams containing cannabinoids could be effective in the treatment of eczema, psoriasis, atopic and contact dermatitis. Researchers from the University of Colorado Anschutz Medical Campus reviewed literature on the subject, in which one study found participants who used cannabinoid cream for three weeks completely eliminated severe itching, likely due to the anti-inflammatory properties of cannabinoids. Senior author Dr. Robert Dellavalle says, “Perhaps the most promising role for cannabinoids is in the treatment of itch." However, because most of the studies included in the report involve animal models, there remains the need for more substantial double-blind clinical trials performed at large scales on human models. Still, Dellavalle believes cannabinoid formulas without psychotropic effects could be a good treatment option for those who have not found relief with more common medications. 

This information has been provided by Civilized and approved by our Chief Medical Officer.