What Are The Medical Benefits of CBD? - Part 2

Photo Credit: NeedPix (https://bit.ly/2XK0i4H)

Photo Credit: NeedPix (https://bit.ly/2XK0i4H)

In today’s post, we’ll continue our discussion of which conditions could benefit from CBD treatment.

We’ll begin with Alzheimer’s disease, which scientists believe CBD could treat or even prevent its onset. A 2013 study found CBD prevented the development of amyloid beta plaques, while another study found CBD promoted the growth of new brain cells that were lost to damage caused by the condition, and that it improved symptoms associated with cognitive deficits. The topical application of CBD may treat acne, and studies have found it can reduce inflammation and the production of sebum oil, as well as halt the development of acne. CBD can also help with psoriasis, and studies have found the cannabinoid can prevent the spread of cells that cause the condition’s patches. CBD may also help cancer patients, not only by reducing the nausea and vomiting associated with chemotherapy, but also by preventing the spread of cancer cells and causing cancer cell death. Studies have also found CBD slows the formation of blood vessels within tumors, thereby blocking nutrients from entering the tumor and slowing its growth.

CBD has also been earning a name lately for treating pain and reducing the need for the harmful opiate medications that are traditionally used. Studies have found CBD reduces inflammation and the sensory perception and emotional effects of pain. Research suggests CBD is more effective at treating long-term neuropathic pain than short-term pain. CBD may protect against heart disease, and studies have found the cannabinoid protects cardiac cells when blood supply to the heart is blocked, stops heart arrhythmia, and reduces cardiac damage when oxygen is block. CBD also reduces heart disease from diabetes by reducing inflammation, oxidative stress, scarring, and cell death. The topical application of CBD can target localized areas of pain caused by arthritis. Studies have found CBD blocks pain and prevents nerve damage from osteoarthritis, as well as uses anti-inflammatory and immunosuppressive effects to blog the condition’s progression. Some studies have found CBD may be able to stabilize mood, something that could be helpful for those suffering from Bipolar Disorder. That said, CBD was only effective during depressive stages, and not during manic phases.

That’s not all! Stay tuned for tomorrow’s post to learn more about which conditions CBD could help. This information has been provided by Leaf Science and approved by our Chief Medical Officer.

What Are The Medical Benefits of Marijuana? - Part 3.

Photo Credits: Leaf Science

Photo Credits: Leaf Science

In the last post, we continued to look at the conditions where medical marijuana is effective. It’s not done yet! We’ll continue the discussion below.

While the relationship between marijuana and heart disease is complicated, and cannabis can actually exacerbate symptoms in some users by increasing heart rate and blood pressure, scientists have found low doses of THC can reduce damage from heart attacks, and CBD can be used as a treatment for cardiovascular disease. Cannabis may also reduce the severity and lessen the impact of a stroke. Although most studies thus far have been animal studies, researchers believe medical cannabis may help treat the symptoms of Huntington’s disease, and one human study found synthetic THC improved motor-related symptoms of the disorder. Animal studies have found cannabis may slow the progression of Amyotrophic lateral sclerosis, and many properties of cannabis could help reduce pain, relax muscles, reduce saliva, stimulate appetite, and induce sleep. Synthetic cannabinoids also improved pain symptoms in fibromyalgia patients, and one survey found patients actually preferred cannabis to any approved pharmaceutical medication.

New support is starting to accumulate for the use of marijuana for Alzheimer’s disease. Marijuana may be able to do so by reducing inflammation and the formation of plaques. Marijuana has been found to alleviate tics and be well tolerated in patients with Tourette’s syndrome. Cannabis topicals are now offered as effective treatments for varying skin disorders, and its anti-inflammatory and anti-itching properties make it effective for the treatment of acne, dermatitis, and psoriasis. Marijuana may also help those who suffer from sleep disorders like insomnia and sleep apnea fall asleep quicker and improve breathing during sleep. Lastly, and probably most well known, is medical marijuana’s ability to treat epilepsy. Specifically, the cannabinoid CBD is well-tolerated and effective in reducing the frequency and severity of seizures.

There are even many more conditions to talk about regarding medical marijuana treatment. Keep reading as we conclude our discussion in the next post! This information has been provided by Leaf Science and approved by our Chief Medical Officer.

Research Finds Cannabinoids May Help Treat Certain Skin Diseases

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

A new research review conducted by researchers at the University of Colorado Anschutz Medical Campus suggests the anti-inflammatory properties found in cannabinoids may be able to soothe skin conditions like psoriasis, eczema, atopic and contact dermatitis, and even melanomas. Headed by Dr. Robert Dellavalle, MD, researchers looked at literature surrounding cannabinoids and skin conditions. In one study, cannabinoids that were injected into skin tumors in mice prevented the growth of the tumors. Another study found THC reduced swelling and inflammation in mice. In yet another study, 8/21 patients who used cannabinoids topically twice a day over the course of three weeks witnessed symptoms of itching eliminated. Through topical applications, active compounds penetrate and are absorbed through the skin, where they can interact with nearby cells' receptors without providing any psychotropic effects. 

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. 

What Can't It Do? Study Suggests Cannabis Could Help Treat Various Skin Diseases

Photo Credit: Civilized 

Photo Credit: Civilized 

A report published in in the Journal of the American Academy of Dermatology suggests  topical creams containing cannabinoids could be effective in the treatment of eczema, psoriasis, atopic and contact dermatitis. Researchers from the University of Colorado Anschutz Medical Campus reviewed literature on the subject, in which one study found participants who used cannabinoid cream for three weeks completely eliminated severe itching, likely due to the anti-inflammatory properties of cannabinoids. Senior author Dr. Robert Dellavalle says, “Perhaps the most promising role for cannabinoids is in the treatment of itch." However, because most of the studies included in the report involve animal models, there remains the need for more substantial double-blind clinical trials performed at large scales on human models. Still, Dellavalle believes cannabinoid formulas without psychotropic effects could be a good treatment option for those who have not found relief with more common medications. 

This information has been provided by Civilized and approved by our Chief Medical Officer. 

 

Medical Marijuana for Psoriasis

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

Psoriasis is an autoimmune skin disorder that causes dry, flaky, and red rashes, and at times leads to psoriatic arthritis. It is believed that autoimmune disorders may be the result of a disruption in the endocannabinoid system, so it is plausible that the cannabinoids found in cannabis may be able to counteract this disruption in order to help better manage psoriasis. Studies suggest when cannabinoids interact with CB2 receptors, they are able to prevent psoriasis flare-ups. Additionally, their anti-inflammatory effects and ability to regulate the immune system could prove beneficial for psoriasis therapy. Other studies have found cannabinoids can manage proliferation of skin cells, and cannabinoid receptors regulate T cell activity. Lastly, THC, CBD, CBN, and CBG are all cannabinoids that inhibit overactive T cells, making them important for psoriasis therapy. 

This information has been provided by Medical Marijuana Inc. and provided by our Chief Medical Officer. 

Can Cannabis Treat Psoriasis?

Photo Credit: Getty

Photo Credit: Getty

Humans have a skin-specific endocannabinoid system within the subcutaneous dermis that plays a vital role in skin cell differentiation, proliferation, growth, apoptosis, and hormonal or the production of other skin cell types and appendages. This allows cannabinoids to treat skin conditions like psoriasis and pruritis. Psoriasis is a chronic inflammatory skin disease characterized by uncontrolled epithelial skin cell growth, which can results in itching (pruritis) and raised flaky scales. Other symptoms include redness, dryness, swelling, pain, burning, soreness, and discomfort. 

One study found some cannabinoid receptors in the skin have an affinity to anandamide, which is an endogenous CB receptor ligand that is responsible for inhibiting epidermal keratinocyte differentiation and proliferation. Another study found THC, CBD, CBG, and CBN all inhibited rapid proliferating skin cells. While these cannabinoids may not stop the process completely, they can slow it down. Cannabinoids also modulate immune responses in psoriasis pathology by regulating T-helper subset cells to correct cytokine release, and decreasing anti-inflammatory molecules via CB1 receptor mechanisms. In addition to treating the symptoms of psoriasis directly, cannabinoids' anti-allergic, anti-microbial, and antioxidant properties that could help benefit psoriasis patients.

Topical applications of cannabinoids are recommended because they are absorbed directly through the skin, which helps them control immature skin cell production and inflammation. If you're using cannabinoids to treat psoriasis, we'd like to learn about it! Document your dosing regimen anonymously in the journal section of our app. In doing so, you will contribute to a better understanding of how cannabinoids target psoriasis symptoms. This information has been provided in part by The Marijuana Times and approved by our Chief Medical Officer. 

Treating Psoriasis with Topical Cannabis

Photo Credit: Whaxy

Photo Credit: Whaxy

The use of topical cannabis can provide relief for medical marijuana patients who suffer from skin conditions, joint issues, and muscle problems. Topicals come in the form of creams, oils, lotions, sprays, balms, or ointments, deliver cannabinoid relief through absorption in the epidermis, and can provide isolated cannabinoid relief or the benefits of whole plant cannabis without producing a psychoactive effect. In fact, even topicals infused with THC will not provide a psychoactive effect when absorbed through the skin.

Topicals for the treatment of skin conditions is welcomed news for those who suffer from psoriasis, a condition in which skin cells develop rapidly on the surface of the epidermis resulting in thick discolored plaques. Psoriasis is caused by problems with the immune system and produces inflammation, which is how cannabis can effectively treat the condition through interacting with the endocannabinoid system. Most information surrounding cannabis as a treatment for psoriasis is anecdotal, but one 2007 study found cannabinoids prevented dead skin cell buildup and other symptoms of psoriasis. Researchers stated, "Our results show that cannabinoids inhibit keratinocyte proliferation, and therefore support a potential role for cannabinoids in the treatment of psoriasis."

While this information is positive, further clinical research is left to be desired. This information has been provided by Whaxy and approved by our Chief Medical Officer.