What Are The Medical Benefits of CBD? - Part 1

Photo Credit: NeedPix (https://bit.ly/2XK0i4H)

Photo Credit: NeedPix (https://bit.ly/2XK0i4H)

As legalization proceeds and barriers to medical marijuana research are knocked down, we are becoming more aware of just how powerful wide-reaching medical marijuana is. One of the cannabinoids getting the most attention is cannabidiol (CBD), a non-psychoactive cannabinoid that can help a myriad of conditions. In this series, we will discuss some of the many conditions CBD can treat.

Numerous studies have suggested CBD can reduce anxious feelings in those with anxiety disorders, and that it can effectively treated a variety of anxiety disorders, including OCD, panic disorder, generalized anxiety disorder, PTSD, and social anxiety disorder. Studies also suggest CBD could benefit those who suffer from depression. Animal studies have shown CBD acts on the serotonin pathways in the brain, allowing it to act as an antidepressant, and one study found CBD reduces anhedonia, which is a symptom of depression that prevents people from feeling joy or happiness. CBD can also stop nausea and vomiting. One study found CBD effectively helped treat nausea in patients who did not get relief from traditional treatments. CBD may also help those with diabetes, and animal studies have found the cannabinoid slows the progression of diabetes and diabetic inflammations, as well as benefit complications associated with diabetes. CBD may also protect against diabetes, and one study found CBD prevented at-risk mice from developing the condition.

Perhaps the most well-known success story for CBD is its ability to treat epilepsy. CBD has acted as an anticonvulsant in animal models, and GW Pharmaceuticals have been testing their CBD oil Epidiolex with success. In the study, 25 and 50 mg/kg a day lowered seizure frequency by half while producing few mild side effects. Additionally, a 2013 survey of parents of children with treatment-resistant epilepsy found 84% reported reduced seizure frequency with CBD use. Lastly, and contrary to previous beliefs, CBD may treat schizophrenia and mental illnesses related to psychosis. It has been found to be as effective as antipsychotics with fewer side effects, and scientists believe this could be attributed to the stimulation of anandamide production. One study found CBD helped with hallucinations, delusions, lack of emotion, and reduced social functioning. CBD can also benefit those with Parkinson’s disease, and various studies have found CBD can help treat the sleep disturbances and psychosis associated with the disorder without worsening motor symptoms and while improving overall quality of life.

This information has been provided by Leaf Science and approved by our Chief Medical Officer. In tomorrow’s post, we will continue to discuss some of the conditions CBD is able to treat.

What Are The Medical Benefits of Marijuana? - Part 3.

Photo Credits: Leaf Science

Photo Credits: Leaf Science

In the last post, we continued to look at the conditions where medical marijuana is effective. It’s not done yet! We’ll continue the discussion below.

While the relationship between marijuana and heart disease is complicated, and cannabis can actually exacerbate symptoms in some users by increasing heart rate and blood pressure, scientists have found low doses of THC can reduce damage from heart attacks, and CBD can be used as a treatment for cardiovascular disease. Cannabis may also reduce the severity and lessen the impact of a stroke. Although most studies thus far have been animal studies, researchers believe medical cannabis may help treat the symptoms of Huntington’s disease, and one human study found synthetic THC improved motor-related symptoms of the disorder. Animal studies have found cannabis may slow the progression of Amyotrophic lateral sclerosis, and many properties of cannabis could help reduce pain, relax muscles, reduce saliva, stimulate appetite, and induce sleep. Synthetic cannabinoids also improved pain symptoms in fibromyalgia patients, and one survey found patients actually preferred cannabis to any approved pharmaceutical medication.

New support is starting to accumulate for the use of marijuana for Alzheimer’s disease. Marijuana may be able to do so by reducing inflammation and the formation of plaques. Marijuana has been found to alleviate tics and be well tolerated in patients with Tourette’s syndrome. Cannabis topicals are now offered as effective treatments for varying skin disorders, and its anti-inflammatory and anti-itching properties make it effective for the treatment of acne, dermatitis, and psoriasis. Marijuana may also help those who suffer from sleep disorders like insomnia and sleep apnea fall asleep quicker and improve breathing during sleep. Lastly, and probably most well known, is medical marijuana’s ability to treat epilepsy. Specifically, the cannabinoid CBD is well-tolerated and effective in reducing the frequency and severity of seizures.

There are even many more conditions to talk about regarding medical marijuana treatment. Keep reading as we conclude our discussion in the next post! This information has been provided by Leaf Science and approved by our Chief Medical Officer.

Medical Marijuana and Epilepsy

Photo Credit: Leaf Science/ShutterStock

Photo Credit: Leaf Science/ShutterStock

There is growing evidence suggesting medical marijuana could be a powerful agent in combatting epilepsy, even in its most severe and treatment-resistant forms, and its symptoms. Marijuana acts as an anticonvulsant, and produces antiepileptic effects through its interactions with both the CB1 and CB2 receptors. In recent years, GW Pharmaceuticals has been conducting experiments that have proven their pure CBD extract effectively reduces the frequency and severity of seizures in severe treatment-resistant forms of epilepsy.

Most researcher attribute cannabis’ therapeutic effects for epilepsy to the cannabinoid cannabidiol (CBD). CBD is a non-psychoactive, making it appropriate for use in pediatric care, and it produces very few mild side effects, like dry mouth, diarrhea, sleepiness, and fatigue. CBD can work on its own or work as a powerful supplement to other epilepsy medications, but it may interfere with the processing of other medications in the liver, so patients who choose to use the medication should research its interactions with other medications before beginning a CBD regimen. There is less information regarding the use of tetrahydrocannabinol (THC) for epilepsy, which is a cannabinoid known for its psychocactive activity, and some reports suggest it may exacerbate symptoms. That said, THC may also act as an anticonvulsant, so some researchers think including some amounts of it in one’s regimen may provide optimal relief. In one study, ratios of 20:1 CBD to THC produced maximum seizure relief in patients. More research is needed to better understand which cannabinoids and the amount of each can produce the best relief with the lowest side effects.

This information has been provided by Leaf Science and approved by our Chief Medical Officer.

Study Reveals CBD Reduces Kids’ Seizures by 50 Percent

Photo Credit: MassRoots

Photo Credit: MassRoots

A new study conducted by the American Academy of Neurology found CBD decreased atonic seizures (commonly known as "drop" seizures) by as much as 50% in patients suffering from a specific and severe form of epilepsy known as Lennox-Gastaut Syndrome (LGS). The study involved 225 participants with LGS who experienced an average of 85 atonic seizures per month and who had tried an average of six epilepsy medications without finding relief. During the study, each patient also took an average of three epilepsy medications. The patients were divided into three groups, in which one group was given 20 mg per kg of body weight, while another received 10 mg/kg, and the last group received placebo. 

Of the first group, 42% saw a reduction in atonic seizures, with 40% of them saying their seizures were cut in half. Of the second group, 37% experienced a reduction, with 36% of them saying their seizures were cut in half. The placebo group experienced a 17% reduction in atonic seizures, with 15% saying their seizures were cut in half. While side effects were reported, they were mild and consisted of drowsiness and a limited appetite. All in all, those who took CBD treatment were 2.6 times more likely to report an improvement in their conditions.

Author of the study Anup Patel, MD, of Nationwide Children's Hospital and the Ohio State University College of Medicine, explains, “Our results suggest that cannabidiol may be effective for those with Lennox-Gastaut syndrome in treating drop seizures... This is important because this kind of epilepsy is incredibly difficult to treat. While there were more side effects for those taking cannabidiol, they were mostly well-tolerated. I believe that it may become an important new treatment option for these patients.”

This information has been provided by MassRoots and approved by our Chief Medical Officer. 

Cannabis Reduces Seizures in 9/10 Adults With Epilepsy, Survey Finds

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

According to a nationwide Australian survey involving 976 respondents and published in Epilepsy & Behavior, cannabis effectively reduced seizures in both children and adults. The study, called the Epilepsy Action Australian study, found 14% of patients with epilepsy had used cannabis for treatment, and of those patients, 90% of adults and 71% of parents or guardians of children with epilepsy found cannabis reduced the frequency of seizures. The study found a correlation between past anti-seizure drugs and medical cannabis use in both adults and children, in that with every anti-seizure medication tried in the past, patients were 1.1 times more likely to experiment with cannabis as an alternative treatment. All respondents noted their main reasons for trying medical marijuana products was in an attempt to better manage their seizures that had proven resistant to traditional pharmaceutical options, and they hoped for a regimen with fewer and more favorable side effects.

The study's lead author, Anastasia Suraey, wrote, “Despite the limitations of a retrospective online survey, we can not ignore that a significant proportion of adults and children with epilepsy are using cannabis-based products in Australia, and many are self-reporting considerable benefits to their condition.” Co-author Carol Ireland added, “This highlights a growing need to educate consumers and health professionals on the use of cannabis by people with epilepsy, and to provide safe and timely access to cannabinoid medicine in order to lessen people’s reliance on illicit black market products.” This study partnered with the Lambert Initiative at the University of Sydney. 

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. Find text of the study here

Clinical Study Confirms Effectiveness of CBD as Treatment for Seizures

Photo Credit: Pixabay

Photo Credit: Pixabay

Medical Marijuana Inc. recently released the results of a clinical trial involving CBD-based Real Scientific Hemp Oil for relief from Lennox Gastaut Syndrome (LGS). LGS is described as severe childhood encephalopathy that produces frequent seizures and cognitive impairment, and it had previously been considered treatment-resistant to conventional therapies. Recently, however, researchers have found CBD to be a more successful treatment option. This new study from Medical Marijuana Inc. found RHSO-X 5000 reduced seizures for 84% of their patients, and over half of the patients reported their seizures reduced by 75%. Another 17% of patients reported becoming seizure free. Additionally, 89% of patients reported an improved quality of life without experiencing negative or severe side effects. 

This information has been provided by Merry Jane and approved by our Chief Medical Officer. 

Conditions Medical Marijuana Could Help

Photo Credit: Medicinal Marijuana Association

Photo Credit: Medicinal Marijuana Association

Medical cannabis is full of chemical compounds called cannabinoids and terpenes that interact with the body's endocannabinoid system. The different concentrations of compounds allow the plant to have a wide array of different effects, which make cannabis suitable for many different conditions and symptoms, or even combat the side effects of other treatment regimens. For cancer patients undergoing chemotherapy, cannabis can alleviate side effects associated with the treatment like fatigue, nausea, pain, loss of appetite, and insomnia. Similarly, HIV/AIDS treatment regimens produce similar side effects that can be alleviated by medical cannabis. 

Patients who suffer from multiple sclerosis experience neurological problems and muscle spasms. Medical Cannabis can help alleviate these symptoms, which can allow patients to gain control over their muscles, regain bladder control, improve vision and mobility, and thereby improve their overall quality of life. Cannabis can help those with epilepsy by reducing the frequency of seizures and even, at times, eliminating them all together. Studies have found CBD is an effective treatment option even in those who suffer from forms that had previously proven treatment-resistant. Chronic pain accompanies a wide range of conditions, but research has found cannabis can be as effective as pharmaceutical options. This offers patients a safer alternative to dangerous pharmaceuticals like opioids. Lastly, some patients with depression or anxiety could benefit from the relaxing properties high-CBD strains of cannabis. 

This information has been brought to you by the Medicinal Marijuana Association and approved by our Chief Medical Officer. 

 

Does Marijuana Actually Help Relieve Pain?

Photo Credit: Medicinal Marijuana Association

Photo Credit: Medicinal Marijuana Association

Medical marijuana is being touted as a powerful analgesic that is as effective as traditional pharmaceuticals and opioids but with a much higher safety profile. Marijuana is effective in treating both acute and chronic pain, and it is a good alternative to traditional treatment options for those who are looking for a long-term solution and new pain management option. Pain is often a symptom of other conditions, so medical marijuana could be helpful for those who are looking to treat pain as a result of MS, migraines, diabetes, and epilepsy. Medical marijuana can change one's perception of pain, affecting how the brain interprets it and how the body reacts to painful stimuli. 

Medical marijuana is able to provide these therapeutic benefits thanks to its chemical properties like cannabinoids and terpenes. The chemical makeup and composition of specific medical marijuana strains determine the effects of the medication, which can range from stimulating bone growth, killing cancer cells, controlling muscle spasms, increasing appetite, and reducing nausea. 

This information has been provided by the Medicinal Marijuana Association and approved by our Chief Medical Officer. 

Study: Epileptic Patients Report Subjective Benefits from Cannabis

Photo Credit: The Daily Chronic

Photo Credit: The Daily Chronic

It's no hidden secret that cannabis and its cannabinoid CBD are gaining in popularity for the treatment of epilepsy. Data published in the journal Epilepsy & Behavior now reveals most patients with epilepsy report experiencing subjective benefits following the use of cannabis. Canadian researchers pooled more than 300 adult patients admitted to an epilepsy monitoring unit for 14 months. Over half admitted to trying cannabis and over a third had used it in the past year, and they associated cannabis use with perceived reductions in seizure frequency and stress, and improvements sleep and memory/concentration. These findings support clinical findings regarding CBD's powerful anti-convulsant benefits.

In order to substantiate safety and efficacy, formal clinical studies and daily patient journaling with the CannaBest Medical app are recommended. This information has been provided by the Daily Chronic and approved by our Chief Medical Officer. 

MMJ for Neurological Disorders - Part 1

Photo Credit: Medical Marijuana Inc. 

Photo Credit: Medical Marijuana Inc. 

Neurological disorders refers to over 600 disorders that attack the body's nervous system, affecting the brain, spinal cord, and nerves. Neurological disorders can cause muscle weakness, loss of muscle control or poor coordination, paralysis, loss of sensation, spasms, seizures, loss of mental control, loss of consciousness, confusion, and pain. Cannabis has neuroprotective properties that support brain health, spinal cord and nerve health, and prevent or limit the progression of certain disorders. Cannabinoids in cannabis protect neurons, mediate inflammatory responses, and encourage regeneration. Cannabis may halt the progression of neurological disorders, delay their onset, and manage associated symptoms like spasms, seizures, tics, pain, and more. Because there are so many disorders considered neurological, we will divide this post in to a two part series. 

The cannabinoid CBD has been shown to delay the onset of the neurological disorder Amyotrophic Lateral Sclerosis (ALS), prolong the neuron survival, and halt ALS progression. Additionally, cannabis has properties that can help manage ALS symptoms of pain, appetite loss, depression, sleeping issues, spasticity, and drooling. Countless studies have shown CBD can help reduce or even eliminate seizures in those who suffer from another neurological disorder: epilepsy. Cannabinoids also help those who suffer from migraines by inhibiting the pain response through the activation of CB1 and CB2 receptors. Lastly, cannabis-based medicines have proven effective at reducing chronic neuropathic pain that are unresponsive to traditional treatments.

This information has been adapted from Medical Marijuana Inc. and approved by our Chief Medical Officer. Stay tuned for part two of the series!