Epidiolex Shows Promise in Latest Study

Photo Credit: Marijuana Investor News

Photo Credit: Marijuana Investor News

The latest study surrounding Epidiolex, a CBD-derived medication produced by GW Pharmaceuticals, has shown promising results in the treatment of intractable seizures. The trial lasted three months and involved 313 children who suffered from seizure disorders and did not experience relief from conventional treatment methods. The ages of the children varied, but the average age was about 11 years old. Participants were given Epidiolex in addition to their regular medications, and approximately 84% of the children witnessed a reduction in grand mal seizures by an average of about 50%. Lead author of the study, Dr. Orrin Devinsky, said 9% of all of the patients, and 13% who suffered from Dravet Syndrome specifically, became seizure free, something that they had never been before.

That being said, the new medication did not work for everyone. About 16% of participants eventually withdrew from the study due to a lack of improvement or to adverse side effects like diarrhea, fatigue, decreased appetite or altered liver enzymes. In addition, the study is not without its limitations. Researchers and participants knew what medication was being administered, which at times produces biased results. The study also neglected to include a control group to look at whether or not a placebo effect was involved. In order to get a truly accurate study, Epidiolex should be researched within a double-blinded and controlled study. Nonetheless, researchers are still hopeful about the medication and hope to continue their research.

This information has been provided by Marijuana Investor News and approved by our Chief Medical Officer.

CannaBit: Gender Gap in Medical Marijuana Program Participation

Image Credit: Marijuana Investor News

Image Credit: Marijuana Investor News

The Marijuana Investor News CannaBit displayed above reveals there is unequal participation between genders throughout different legalized medical marijuana programs. While women account for approximately half of the population in the United States, only 1/4 to 1/3 of certified medical marijuana patients in different states with medical marijuana laws are women. This information is significant because it highlights the need to engage and educate women on the potential therapeutic benefits of medical marijuana. There are various illnesses that, for one reason or another, disproportionately affect women over men, and many of the symptoms of these diseases could be alleviated with the use of medical marijuana. Some of the conditions that are more common among women and could benefit from the use of mmj therapy include, but are not limited to, multiple sclerosis, breast cancer, lupus, depression, and irritable bowel syndrome. With the implementation of medical marijuana programs, women suffering from these conditions have a new option for targeting and alleviating their symptoms, all that's needed is their participation.

This information has been approved by our Chief Medical Officer. 

Must Everybody Get Stoned? Getting Juiced Takes on New Meaning

Photo Credit: Marijuana Investory News

Photo Credit: Marijuana Investory News

For many medical marijuana patients, the point of marijuana consumption is for symptom relief and not for the psychoactive effects that give the plant its recreational reputation. Non-psychotropic strains high in CBD are gaining in popularity, and its demand sometimes outreaches supply, so what is a patient to do if he or she encounters a situation where there are no high-CBD strains available, or where the strain composition is simply untested or unknown? For situations like these, a patient can use a method of consumption called "juicing," in which the cannabinoid THC remains in its acidic state, Tetrahydrocannabinolic Acid (THC-A). 

THC, the cannabinoid responsible for creating a psychoactive experience, is only produced once the chemical compound changes state through a process called decarboxylation when heat is applied. Therefore, when no heat is applied to marijuana, THC-A remains in its natural acidic state and remains lacking in psychoactive properties. Some research labs claim THC-A is "strongly anti-inflammatory, encourages appetite, is anti-tumor, combats insomnia, and is antispasmodic," making it an effective chemical compound for the treatment of various illnesses. In order to consume these acidic cannabinoids without altering their states, some patients have started turning their medication into a drinkable juice. The downside to juicing cannabis, however, is that a large supply of plant material is necessary in order to produce only small amounts of juice. Juicing marijuana is not a cost-effective method of consumption, especially for the budget conscious patient who has other expenses to worry about, but it is certainly one way to avoid getting "high." 

This information has been brought to you by Marijuana Investor News and approved by our Chief Medical Officer. 

Overdoses Involving Selected Drugs in Ohio

Credit: Marijuana Investor News

Credit: Marijuana Investor News

The above chart provided by New Frontier Data and Marijuana Investor News zeroes in on the drug epidemic in Ohio. The chart shows a staggering increase in unintentional overdoses from various drugs between 2002 and 2013. While this chart isolates the problem in Ohio, it mirrors the opioid drug epidemic that is affecting the nation as a whole. This information is significant because not only is it nearly impossible for someone to overdose on marijuana, but studies have shown marijuana has the ability to curb this epidemic. Research has revealed patients are able to use, and in fact prefer, the use of medical marijuana as a substitute for prescription opioid medications in the treatment of symptoms like chronic pain.

This information is brought to you by Marijuana Investor News and approved by our Chief Medical Officer. 

Yale Study Finds Negative Outcomes for Marijuana Users With PTSD

Photo Credit: The Daily Chronic

Photo Credit: The Daily Chronic

One of the biggest forces behind the medical marijuana movement is allowing veterans who suffer from PTSD access to cannabis, but not everyone supports its use in treating the disorder. In contrast to the anecdotal evidence and a few smaller studies supporting the use of marijuana for PTSD, a recent study from Yale University discovered a link between marijuana use and higher levels of PTSD, alcohol abuse and violent behavior. Researchers analyzed data from 2,276 military veterans who completed specialized Veterans Affairs Treatment programs, and dividing the participants into four groups: "never users" who never used marijuana, "continuing users" who used marijuana before and after treatment, "starters" who used marijuana after treatment, and "stoppers" who stopped the use of marijuana after treatment. Researchers looked at PTSD symptom severity, violence, alcohol abuse, and drug abuse, and found "never users" and "stoppers" had the most positive outcomes with lower levels in all four categories. 

The lead researcher Samuel Wilkinson admitted they did not find a causal relationship between marijuana and PTSD, but he hoped the study would encourage people to use caution before jumping to marijuana for the treatment of PTSD. Many will be quick to make the judgment that this study reveals marijuana is ineffective when it comes to treating PTSD. PTSD is an indication for cannabis use in several states, and with the accumulation of data on such patients through research tools like our CannaBest Medical app for smartphones, perhaps the true answer can be established.

This information is provided by Marijuana Investor News and approved by our Chief Medical Officer. 

New Study Confirms Patients Substitute Cannabis for Rx Drugs

Photo Credit: Marijuana Investor News

Photo Credit: Marijuana Investor News

The use of medical marijuana as a substitute for opioids and other pharmaceutical medications has become a hot topic lately as the opioid substance abuse has reached new heights, and evidence supporting this substitution continues to mount. A study conducted by the Centre of Addictions Research of British Columbia and published in the journal Drug and Alcohol Review found 80.3% of the 473 medical marijuana patients examined reported substituting cannabis for prescription drugs, especially those using prescriptions to treat pain.

These new findings support previous studies that found patients preferred cannabis over their prescription medications. Within these various studies, patients cited cannabis as having greater effectiveness in symptom relief, fewer unpleasant side effects, less withdrawal potential, and a reduced risk for addiction. Currently, the United States faces a problem of overprescription and overuse of opioid medication, which can lead to substance abuse and dependency. Access to medical marijuana would not only provide patients effective symptom relief without unwanted side effects, but it would also impact the substance abuse epidemic facing the nation.

This information is brought to you by Marijuana Investor News and approved by our Chief Medical Officer. 

Marijuana 101: Methods of Consumption

Beginning the use of medical marijuana therapy can be confusing and all around overwhelming. Where traditional pharmaceuticals often come in the form of a pre-measured pill with a select composition of ingredients and a specific regimen, medical marijuana patients have to choose their strain and material, determine the amount per dose, create a dosing regimen, and select a method of consumption. All of these factors can be daunting, but thankfully Marijuana Investor News has taken the time to at least break down the methods of consumption to help make your vehicle selection easier. 

The traditional method most widely associated with marijuana is smoking. This method involves using a pipe, water bong, or a joint/blunt to smoke the dried flower or leaves of the marijuana plant. The effects of smoking are often felt instantly, and can last between an hour and a half and four hours depending on strain potency. Smoking marijuana is considered safe, but smoke inhalation of any kind can have negative effects on the lungs, which makes smoking one of the less healthy options for marijuana consumption.

Another popular method involves eating cannabis infused food products. Generally, cannabinoid extracts are infused in butters and oils that then used to create edible products. The most popular and widely available edibles are baked products. This method of consumption is not instant, however, and the effects can take half an hour to two hours before they kick in at all. Because the effect is gradual, patients should use caution when consuming edibles and remember to avoid overconsumption. 

A method of consumption similar to smoking and gaining in popularity is vaporization. While both smoking and vaporizing involve inhalation, vaporization involves inhaling water vapor, which is less harmful on the lungs and nearly eliminates carcinogens from the equation. Vaporizers heat dried marijuana or marijuana oils at low temperatures, allowing active cannabinoids like THC and CBD to convert into vapor. The effects of vaporization are similar to the effects of smoking.

One method that is not widely known is the application of infused topical solutions (like sprays, creams, lotions, oils, or balms). Topicals are non-psychoactive, so patients seeking therapeutic effect without the high often apply marijuana-infused topicals to treat joint inflammation, muscle pain and headaches, and more.

The last method Marijuana Investor News discusses is the tincture, which is a mixture plant extract in an alcohol solution. Tinctures are generally dosed as a few droplets and placed under the tongue or in a beverage. Tinctures are generally very potent and may take a while to take effect. 

Want to know more? Visit Marijuana Investor News for the lowdown on each vehicle for marijuana consumption. 

Study Finds Marijuana Use May Lead to Pre-Diabetes

Photo Credit: Marijuana Investor News

Photo Credit: Marijuana Investor News

Medical marijuana is being hailed as a miracle drug, but as with all medications, cannabis isn't perfect and reacts with everyone differently. Now, there is a study that suggests marijuana use may lead to pre-diabetes, meaning those who are genetically predisposed to the disorder or who live a lifestyle that may bring about diabetes should use cannabis with caution. That being said, while there exists a link between marijuana and pre-diabetes, there is no evidence of a link between marijuana use and the actual development of type-2 diabetes.

The study published in Diabetologia found heavy marijuana use increases a person's risk of developing pre-diabetes. Researchers looked at data from the Coronary Artery Risk Development in Young Adults study, a study that spanned three decades and included 3,000 black and white participants between 32-50 years of age who lived in various United States cities. Participants were surveyed over the phone, examined periodically, and asked to complete detailed questionnaires about their health and lifestyle. 

Marijuana Investor News discusses the study, saying, "Researchers found that individuals who reported current marijuana use faced a 65 percent increased risk of developing pre-diabetes. Those that used marijuana 100 times or more in their lifetime were found to have a 49 percent increased risked of pre-diabetes." Interestingly enough, however, researches did not find a link between marijuana use and the development of type-2 diabetes. In fact, certain surveys suggest a negative association between marijuana use and the development of type-2 diabetes. Additionally, marijuana users typically had a lower BMI than non-users, and higher BMIs are often associated with diabetes. 

Researchers think marijuana use and diabetes should be investigated further, saying "These results contrast with previous findings on marijuana use and metabolic health... future studies should aim to objectively measure the mode and quantity of marijuana use in relation to prospective metabolic health."

Read the full article on Marijuana Investor News. 

Study Shows Link Between Medical Marijuana and Seizure Prevention

Photo Credit: Marijuana Investor News

Photo Credit: Marijuana Investor News

With all of the claims made by parents of patients who suffer from various seizure disorders or by the patients themselves regarding marijuana's ability to reduce or eliminate seizures, it almost seems common knowledge that the plant has anti-seizure properties. That being said, this anecdotal evidence is only as good as the clinical research that is able to support it, and unfortunately United States drug laws severely limit this research. 

Now, a recent analysis performed by doctors Daniel Friedman and Orrin Devinsky seems to back these claims. The doctors reviewed several clinical trials involving cannabinoids and realized there was potential for treating epilepsy. Friedman explained, "When you look at the combined weight of animal data, it appears that cannabidiol appears to have the most consistent anti-seizure effect." In addition, Epidiolex, which is 99% CBD, reduced seizures by 50% or in 2/5 of all patients in one study, or eliminated seizures by 50% in 137 of 213 patients in another study. 

Even though the current clinical research on medical marijuana is lacking, many medical communities and research foundations are coming out in support of removing barriers and allowing access to the plant for further studying its effects on epilepsy. Even the Epilepsy Foundations expresses an interest in exploring CBD's ability to treat seizure disorders. 

Many states on a local level have enacted CBD-only laws, but these laws seem insufficient, as research suggests cannabinoids work better supplementing each other in what is called the entourage effect. On a national level, the United States still has a long way to go to improve access to medical marijuana and remove barriers to researching it's therapeutic properties. 

Visit Marijuana Investor News to read more about these recent studies that back the claims that  marijuana is an effective way for reducing or eliminating seizures. 


Marijuana May Lower Risk of Bladder Cancer in Men

Photo Credit: Marijuana Investor News

Photo Credit: Marijuana Investor News

There is mounting anecdotal and clinical evidence in support of the use of cannabis for treating cancer, and bladder cancer in men is no exception. A recent study led by Dr. Anil A. Thomas and published in the Journal of Urology examined data collected from 84,170 participants aged 45-69 in the California Men's Health Study cohort. The results suggest marijuana may decrease the risk for bladder cancer in men. 

In the study, researchers looked at demographic lifestyle factors, like the use of tobacco or marijuana, and then linked the information with electronic clinical records. Out of all of the participants, 279 eventually developed bladder cancer, of which 89 participants reported using marijuana in comparison with 190 participants who did not. Researchers adjusted various confounding factors and found that marijuana coincided with a 45% decreased risk of bladder cancer. Tobacco use, both with or without marijuana use, increased the risk for developing bladder cancer.

This study offers support for the use of cannabis for decreasing the risk of developing bladder cancer, but Marijuana Investor News reminds us, "Although these findings will be exciting to some, many scientists will be quick to point out that this is just one study and that more research will need to be conducted." It would be interesting to look at the ways in which marijuana is able to prevent bladder cancer in men, but until the plant is removed from the list of schedule I substances, researching and gathering this information will continue to be difficult. 

For a more detailed look at this study, read the full article on Marijuana Investor News.

Pet-friendly Cannabis: Do Your Research

People are beginning to widely accept the healing properties of cannabis for treating a variety of conditions. The drug has been deemed a "miracle drug" by many, and because it is able to provide symptom relief for so many different conditions, people are beginning to wonder if the plant's power could potentially treat their furry friends that fall ill. A pet is an important part of someone's life, so when this loved one falls ill, people try to do whatever they can to provide relief or save their lives. Marijuana Investor News warns if you're considering cannabis for your pet, do you research first; what works for a human does not always work for another species.  

The options available for treating suffering pets are limited and often come with unwanted side effects, so many pet owners are looking for holistic alternatives like medical cannabis. Research and anecdotal evidence suggest cannabinoids like THC and CBD can be helpful for ailing humans, but THC can actually be dangerous for pets. In dogs, the wrong dosage of THC can cause static ataxia which causes them to lose basic motor functions. While humans have never overdosed on marijuana, overconsumption of the plant for animals can be fatal. 

Current medical marijuana companies focused on providing symptom relief for pets isolate CBD or create synthetic cannabinoids. The medical marijuana industry is still budding across the nation, and when it comes to medical marijuana for pets, there is ample room for growth and development. Marijuana Investor News says, "If an animal's pain can be eased and quality of life improved with a prescription of cannabinoids, it is well worth it to invest in the research and development of these druges to see what combinations, strains, and levels of certain cannabinoids are compatible with our furry friends."

Cannabinoids have the potential to help treat sick animals, but until they are investigated further they need to be handled with the utmost care. Read more about the pet and cannabis dilemma on Marijuana Investor News

Study: Medical Marijuana May Help Heal Broken Bones

Medical Marijuana is some sort of a miracle plant, with properties that can treat a long list of ailments, but who knew it could also help heal broken and fractured bones? A study conducted by Tel Aviv University and published in the Journal of Bone and Mineral Research found that when studying mice with mid-femoral fractures, the ones treated with CBD healed significantly quicker than the ones that were not treated with the cannabinoid. The CBD treatment also resulted in healed bones that were stronger and harder to break. It will be interesting to see what research can find when it expands to treating humans who have sustained a broken bone with CBD. For more on the subject, read this article written by Marijuana Investor News: http://bit.ly/1LqlwYl