Cancer Treatment Providers Accepting of Medical Cannabis Use in Children

Photo Credit: The Daily Chronic

Photo Credit: The Daily Chronic

According to survey data published in the journal Pediatrics, physicians who specialized in pediatric cancer treatment overwhelmingly support the use of medical marijuana as a treatment option. The survey enrolled 288 pediatric oncology providers in Illinois, Massachusetts, and Washington, and 92% of respondents were willing to help children with cancer gain access to medical marijuana. A mere two percent of providers were against all use of medical marijuana in children.

This information has been provided by the Daily Chronic and approved by our Chief Medical Officer.

Study: Minors With Seizures, Chemotherapy-Induced Nausea May Benefit From Cannabis

Photo Credit: Civilized

Photo Credit: Civilized

A new study from Harvard’s Department of Psychiatry suggests medical marijuana may be able to help children and teenagers who suffer from seizures or chemotherapy-induced nausea. In the meta-analysis, which looked through 22 studies involving medical marijuana administration to children and teens, it was found THC improved nausea and vomiting in young chemotherapy patients, and CBD helped reduce seizures. Researchers point to proper dosing in order to avoid concerns that cannabis could hinder motor skills and memory function or produce psychoactive effects. Lead author Dr. Shane Shucheng explains, “Our research supports the AAP’s concerns that cannabis can be harmful to children’s brains… Studies of children and adolescents who use recreational cannabis, particularly frequent use of high potency cannabis over longer periods of time, suggest negative effects on learning, memory, attention, and problem-solving ability.”

This information has been provided by Civilized and approved by our Chief Medical Officer.


Marijuana Can Help Children with Seizures, Cancer Nausea

Photo Credit: pixabay.com

Photo Credit: pixabay.com

A new study published in the journal Pediatrics suggests medical marijuana can treat seizures and reduce chemotherapy-related nausea in adolescents. The study analyzed 22 studies related to the use of marijuana as a therapy for children and young adults, and found THC improved nausea and vomiting in young patients undergoing chemotherapy, which CBD was beneficial for treating seizures. This information is especially welcomed for children who have not responded well to other treatment options. While cannabis was seen as beneficial for young patients suffering cancer or epilepsy, the review did not find promising information regarding its use in pediatrics for the treatment of neuropathic pain, PTSD, and Tourette’s syndrome.

On the other hand, the review found cannabis may present certain harms for young patients, and one of the study’s lead authors, Dr. Shane Shucheng Wong, explains, “Our research supports the AAP’s concerns that cannabis can be harmful to children’s brains… Studies of children and adolescents who use recreational cannabis, particularly frequent use of high potency cannabis over longer periods of time, suggest negative effects on learning, memory, attention, and problem-solving ability.” Because of this, there should be extra care in following proper dosing guidelines. That’s where our CannaBest Medical smartphone app can be extra useful! With it, you can keep track of the amount of cannabis used, the frequency of its use, the cannabinoid composition, and the preferred vehicle for administration, so that you can discover the most appropriate treatment regimen. Journal daily for the most accurate results.

This information has been provided in part by HealthLine and approved by our Chief Medical Officer. The views expressed in this post do not reflect an endorsement by HealthLine for our product.

Study Finds Medical Marijuana Is Helping Kids with Cerebral Palsy

Photo Credit: High Times Magazine

Photo Credit: High Times Magazine

A new study conducted by Tikun Olam at the Wolfson Medical Canter near Tel Aviv, Israel, has found cannabis oil significantly reduced symptoms and improved motor skills, sleep quality, bowel movements and general mood in children suffering from Cerebral Palsy. The study, which started three years ago, involved 4o children between the ages 1-17 with high levels of motor disorders, of which 20 have completed testing, and the majority will continue medical marijuana use as an effective supplement alongside current medications. For the first two months, researchers looked for changes in each child’s condition before allowing them to receive medical marijuana. After two months of stability, the children received cannabis oil orally or through a feeding tube three times a day, as a supplement to their current medications. There were two types of oils containing different proportions of THC and CBD.

Researchers used indexes that evaluated medical marijuana’s effects on spasticity, dystonia, motor changes, mood, sleep, constipation, pain, and quality of life, and found after three to four months, the children’s conditions began to improve. They found medical cannabis to be safe with few side effects, and children experienced the strongest improvements, statistically, in motor function, followed by pain relief and improvements in sleep and bowel movements. They also found THC to be most effective for symptom relief, but because of its psychoactive effects, use CBD to buffer these effects. One of the research managers Lihi Bar-Lev Schleider explains, “The THC’s effect is especially relevant to motor function, whether it’s Parkinson’s disease or other motor symptoms… But the THC is also responsible for the psychoactive effect, so we picked a variety that also has a lot of CBD, which moderates the euphoric effect.”

Researchers now want to determine the most effective vehicle for administering the medication. This information has been provided by High Times and approved by our Chief Medical Officer.

Study Finds CBD Reduces Potentially Fatal Seizures In Children

Photo Credit: Civilized 

Photo Credit: Civilized 

A new study led by Dr. Orrin Devinsky of the NYU Langone Medical Center and published in the New England Journal of Medicine found the liquid form of CBD treatment called Epidiolex reduced the number of seizures in children with severe forms of epilepsy. The 120 children and teenagers from the U.S. and Europe who were involved in the study took a teaspoon of Epidiolex or placebo oil twice a day along with their traditional anti-seizure medications over the course of 14 weeks. Patients who took CBD saw a decrease in serious seizures with convulsions from 12 per month to 6. Three of those patients became seizure free. Those who took the placebo saw no change. Epidiolex did produce some side effects, however, and patients who took the medication experienced more frequent diarrhea, vomiting, fatigue, and sleep disturbances. Additionally, 12 patients removed themselves from the study, nine of which were on the drug and three of which were taking placebo. 

Still, the information is positive, and Devinsky says, "This is the first solid, rigorously obtained scientific data that CBD is a safe and effective treatment for this medical problem." This information has been provided by Civilized and approved by our Chief Medical Officer. 

Review Investigates Cannabinoids for Treating Cancer

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

A recent review of the available literature on cannabinoids and cancer in children published by a team of Israeli scientists in The Israel Medical Association Journal concluded cannabinoids like cannabidiol (CBD) are effective in treating cancer. The team of physicians looked at preclinical evidence of cannabinoids' anti-cancer efficacy, clinical evidence of cannabinoids' anti-cancer efficacy, and cannabinoids' efficacy on pediatric tumors. For preclinical trials, researchers highlighted a 1975 study that found cannabinoids reduced tumor growth in in vitro and in vivo experiences. Tetrahydrocannabinol (THC) was effective against lung cancer. More research from the 2000s found cannabinoids had anti-cancer effects on gliomas and various types of tumors, like prostate, breast, leukemia, lymphoma, pancreas, melanoma, thyroid, colorectal, and heptocellular carcinoma, in animal and cultural models. More research into the cannabinoids' therapeutic mechanisms is desired, but what is known is that they induce cell death, inhibit cell growth, and inhibit tumor angiogenesis invasion and metastasis.

There are fewer clinical trials, but researchers were able to identify a human trial involving nine patients that suggested THC treatments effectively decreased tumor growth and slowed tumor progression. There were no clinical trials involving the anti-cancer effects of cannabinoids on pediatric tumors, but in one preclinical trial, CBD effectively reduced the viability and invasiveness of the aggressive pediatric tumor, neuroblastoma. That same study found THC and CBD effectively treated xenograft tumors in mice, with CBD being the more effective of the two. The review urges for more clinical trials to investigate cannabis' anti-cancer effects. 

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. You can also access the review here.

Study Suggests CBD and THC Help Treat Neuroblastoma in Kids

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

A new study from Israel suggests cannabinoids like THC and CBD could mitigate the multiplication of neuroblastoma, which is primarily a childhood disease. In the study, which was published in Current Oncology, researchers found CBD and THC were able to impede the growth of tumors by reducing their viability and invasiveness, and induce apoptosis. Of the two cannabinoids' anti-tumor effects, CBD was found to be more active.

Researchers used culture and animal models to test the effects of these cannabinoids on neuroblastoma. In the culture models, cells were treated with either cannabinoid or left untreated. In the animal models, mice were induced with tumors via subcutaneous injection, and were then injected with 20 mg/kg THC or 20 mg/kg CBD or left untreated for 14 days. Both models investigated the tumors by measuring and testing viability, cell cycle distribution, growth rate, cell invasiveness, and apoptotic cell death rate. Researchers conclude, “Our findings about the activity of CBD in [neuroblastoma] support and extend previous findings about the anti-tumor activities of CBD in other tumors and suggest that cannabis extracts enriched in CBD and not in THC could be suitable for the development of novel non-psychotropic therapeutic strategies in [neuroblastoma]."

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. 

Randomized Controlled Trial Finds CBD may Reduce Pediatric Seizure Frequency by 50%

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

Researchers at Nationwide Children's Hospital have found cannabidiol (CBD) may be an effective treatment of a rare and severe form of epilepsy. The study, which was randomized, double-blind, and placebo-controlled, involved 225 people with Lennox-Gastaut Syndrome who received a CBD agent free of THC over the course of 14 weeks. Before enrolling in the study, participants had tried an average of 6 traditional anti-epileptic medications without success, and experienced an average of 85 weekly "drop seizures," which occur when the muscles become limp and cause an individual to fall. During the study, patients received either high doses of CBD (20 mg/kg), low doses of CBD (10 mg/kg), or placebo, of which 40% of high-dose patients and 36% of low-dose patients experienced 50% or greater reductions in drop seizures. High-dose patients experienced a decrease in drop seizures by 42%, on average, per week, and low-dose patients saw this decrease by an average of 37%. Those who received CBD were 2.6 times more likely to say their condition had improved than the patients who received placebo and experienced a 17% reduction.

Study author Dr. Anup Patel writes, “Our study found that cannabidiol shows great promise in that it may reduce seizures that are otherwise difficult to control.” Patel noted that those who received CBD were more likely to experience side effects like a decrease in appetite and sleepiness, but that these side effects were mostly well-tolerated.

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. 

Study Shows That Children Absorb Chemicals From Secondhand Cannabis Smoke

Photo Credit: Merry Jane

Photo Credit: Merry Jane

A study authored by pediatrician Dr. Karen Wilson that involved 43 Colorado children aged one month to two years old who were hospitalized for bronchitis suggests children absorb chemicals from secondhand marijuana smoke. Researchers sent urine samples to the Center for Disease Control and Prevention and found 16% of the samples contained low levels of marijuana metabolites, and 75% of the children whose caregivers admitted they had been exposed to marijuana tested positive for traces of cannabis. There is little scientific information concerning the health effects of low traces of cannabis metabolites in children, but parents should keep their cannabis at a safe distance from their children until more research is conducted.

There are also other methods of intake available that do not involve inhalation or the release of smoke or vapor, which include edibles, tinctures, juices or topicals. If you're testing out new vehicles of administration and you're not sure how it will effect your dosing regimen, remember to journal daily on our app! In this way, you'll be able to see how this change affects your symptom relief. Through journaling, you will be able to look back at your new routine to determine whether or not this change in vehicles positively or negatively affected your medical marijuana dosing experience.

This information has been brought to you in part by Merry Jane and approved by our Chief Medical officer. 

Medical Marijuana, for Babies and their Desperate Parents

Photo Credit: CNN

Photo Credit: CNN

For many parents of children with treatment-resistant epilepsy, it can seem like the options for treating their children's affliction have all been exhausted. Medical marijuana, however, is now being hailed as a miracle medication for these young patients. The controversial medicine is still difficult to access in many states throughout the U.S, and many fear medical marijuana could have a detrimental affect on the development of young children. Those parents that do have access to medical marijuana largely tout the benefits of medical marijuana above all other medications they have tried, even saying medical marijuana can lead to the reduction or elimination of other pharmaceutical medications. 

In this CNN feature, dive into an in depth look at medical marijuana for the treatment of young children. In this article, you'll follow the story of a baby born with epilepsy and cerebral palsy and treated with medical marijuana in Israel where cannabis research is far more advanced than in the United States. You'll also learn about the current research surrounding medical cannabis and young children. Read the in depth feature here. This information has been approved by our Chief Medical Officer. 

Landmark Study Confirms Marijuana Extract Is Amazing Aid to Prevent Seizures in Children With Epilepsy

Photo Credit: Alternet

Photo Credit: Alternet

The recent annual meeting of the American Epilepsy Society presented landmark data confirming medical cannabis can be helpful in combatting children. In the United States alone, epilepsy affects one in 26 Americans, one third of those patients having a treatment-resistant form of the condition. The study discussed revealed that of 261 patients who received cannabidiol (CBD) treatment, the non-psychoactive extract provided the best relief for treatment resistant epilepsy. Forty-five percent of those who received the CBD treatment received a significant reduction in seizure frequency, and nine percent were seizure-free after three months. Even after the trial, some children continued to experience the benefits. Lead author of the story, Orrin Devinsky, discusses the significance of this data, saying "In the subsequent periods, which are very encouraging, nine percent of all patients and thirteen percent of those with Dravet Syndrome epilepsy were seizure-free. Many have never been seizure-free before."

This information has been provided by Alternet and approved by our Chief Medical Officer. 

Pot Chemical and Kids' Hard-to-Treat Epilepsy

Photo Credit: Flickr Andres Rodriguez

Photo Credit: Flickr Andres Rodriguez

In a new report to be released at the American Epilepsy Society's annual meeting, researchers say cannabidiol (CBD) reduced seizure disorders in as many as half of the children with epilepsy who participated in its treatment. This could be because the cannabinoid may interact with a receptor in the brain that modulates calcium inside and outside of the neuron, which plays a role in exciting nerve cells and developing seizures.

In one study led by Dr. Orrin Devinsky involving 261 patients averaging around age 11, patients who were resistant to anti-seizure medications received a cannabidiol oil called Epidiolex along with their current drug therapies. After three months, Devinsky witnessed a decline in seizure frequency by about 45% in all study participants. Almost half of the participants experienced greater than a 50% reduction in seizure frequency, and ten patients became completely seizure free. Another study conducted at the University of California in San Francisco, about 25 children suffering from epilepsy received a marijuana-derived oil along with their regular drug regimen for one year. After one year, 10 participants (40% of the group) experienced over 50% reduced seizure frequency. One child became seizure free, but the 12 children dropped out of the study because they did not see positive results. 

While these findings are significant and hopeful, some studies have found CBD oil to actually act negatively with some anti-seizure medications. In order to truly find out how effective CBD is in combatting epilepsy disorder in children, there need to be more placebo-controlled and blinded clinical trials. This information has been brought to you by WebMD and approved by our Chief Medical Officer. 

Study: Adolescent Marijuana Use Not Associated With Health Problems In Early Adulthood

Photo Credit: The Daily Chronic

Photo Credit: The Daily Chronic

One of the strongest debates in the medical marijuana movement is the effect marijuana use will have on children as they develop. This is an especially important issue for caregivers and parents who are treating young children and adolescents for various conditions, and some medical marijuana advocates and opponents alike say there is not enough research surrounding the effects of marijuana on children for its use to be acceptable. Now, research has been published in the journal Psychology of Addictive Behaviors that may put these worries at ease.

Researchers at the Pittsburgh School of Medicine and Rutgers University examined cannabis use by male adolescents and young adults and found the use did not increase the risk for adverse mental and physical health effects later in life. The 20 year study controlled factors like socioeconomic status, the use of alcohol, tobacco, or other drugs, and access to medical care and health insurance. The authors then concluded, "Overall, data from this sample provide little to no evidence to suggest that patterns of marijuana use from adolescence to young adulthood... were negatively related to the indicators of physical or mental health studied."

While this study is a step in the right direction when it comes to continuing marijuana research, a more extensive study that takes into consideration different genders would yield more complete data and is necessary in truly understanding the effects of marijuana on all adolescents. For a more detailed analysis of this study, read this article on Daily Chronic. You can also go straight to the source and read from the Psychology of Addictive Behaviors

Medical Marijuana All But Eliminates Seizures in Texas 9-Year-Old Girl

Photo Credit: www.wfaa.com

Photo Credit: www.wfaa.com

Because medical marijuana is federally a schedule 1 drug, we are often forced to rely on anecdotal evidence of its efficacy due to the fact very few extensive research exists on the medication. Thankfully, there is countless anecdotal testimonies that exist, and it seems these stories are constantly influencing policy makers, making access to medical cannabis easier as states begin to ease up on their medical marijuana laws and pass medical marijuana legislation. 

One such story exists about 9-year-old Alexis Borell who suffered from severe epilepsy that interfered with her life on a daily basis. When her parents began to fear for her life, they decided it was time to move from their restrictive state of Texas to Colorado where medical marijuana was widely available. After the move, the little girl's seizures dropped from a daily occurrence to something that happened approximately once a month. Borell's father said of the 15-part CBD to 1-part THC mixture he used to treat his daughter's symptoms, "we're not seeing symptom reduction. We're seeing symptom elimination."

We hope that these testimonies will push lawmakers towards the path of medical marijuana legalization nationwide so that children like Alexis do not have to move from their home states to seek relief. Hopefully marijuana will be rescheduled so that extensive clinical research can be conducted; these stories should back up medical research, and not be the only evidence we have to rely on. For a more detailed look at Alexis borell's story, read this Whaxy article

Groundbreaking Research Suggests Medical Marijuana Could Reduce Seizures In Children

AP Photo/Brennan Linsley, File

AP Photo/Brennan Linsley, File

For children who suffer from epilepsy and other seizure disorders, there may be a new treatment option approved by the FDA in the near future. The drug Epidiolex, which is derived from cannabidiol (CBD), is the first FDA-sanctioned drug to undergo several clinical trials for the purpose of examining its effects on children who suffer from intractable seizure disorders. The American Academy of Neurology released very encouraging preliminary results from the trials. Data revealed that over 50 percent of 137 epileptic children and young adults who were treated with Epidiolex for a period of three months saw a reduction in their seizures.

These results are only preliminary, and should not be taken as hard scientific proof yet, but now there is research that seems to support what people have been saying all along: medical marijuana can reduce seizures in children. The clinical trials for Epidiolex will continue for several months, and the complete results of the trials should be available next year. 

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