What Is CBDV (Cannabidivarin) And What Does It Do?

Photo Credit: High Times

Photo Credit: High Times

There are over 100 known cannabinoids in cannabis, but many are only familiar with the well-known cannabinoids like cannabidiol or tetrahydrocannabinol. One lesser known cannabinoid is cannabidivarin (CBDV), a non-psychoactive cannabinoid that acts as an antiemetic and anticonvulsant. The cannabinoid is similar structurally to CBD, and like CBD, it may be able to help treat those who suffer from epilepsy and nausea. One study from 2013 found CBDV significantly reduced chemically-induced seizures. Another study from 2014 found the cannabinoid interactive with receptors responsible for detecting and regulating body temperatures and producing pain sensations. The Italian research team also noted CBDV reduced the duration and strength of simulated epileptic seizures in the brains of rats. Lastly, a study from 2013 published in the British Journal of Pharmacology found CBDV may have interacted with CCB1 receptors to reduce nausea in rats. The pharmaceutical company GW Pharmaceuticals is currently conducting clinical trials researching the use of CBDV.

This information has been provided by High Times and approved by our Chief Medical Officer.

Cannabis for Nausea and Vomiting

Photo Credit: Whaxy

Photo Credit: Whaxy

One of the well known healing properties of cannabis is its ability to reduce nausea and vomiting, something that is especially useful for cancer or HIV/AIDs patients undergoing chemotherapy or radiation therapy. Patients experiencing nausea or vomiting don't have much of an appetite, so cannabis' ability to stimulate appetite is also beneficial in targeting nausea and vomiting. While pharmaceutical medications have evolved over time to effectively target nausea and vomiting symptoms, they are generally much more expensive than marijuana and often carry negative side effects that marijuana does not. 

Whaxy stresses the need for more research, but says the studies that do exist show indica strains that contain a lot of the terpene myrcene are especially effective in reducing nausea and stimulating appetite. A 2013 study published in the British Journal of Pharmacology analyzed the effects of the cannabinoids THCV and CBDV in rodents with toxin-induced nausea. The author, concluded both cannabinoids “may have therapeutic potential in reducing nausea.” A review of these studies also suggested THC was able to stimulate appetite in cancer and HIV/AIDS patients.

Another study from the Michigan Department of Health in 1982 looked at 165 cancer patients undergoing chemotherapy who sought to alleviate nausea and vomiting. The participants were divided into groups, one using cannabis and the other using the pharmaceutical drug Torecan. Patients could elect to switch to the other group if they found their treatment ineffective. Of those receiving cannabis, 90 percent continued its use. Out of the 23 patients who received Torecan, 22 opted to switch to cannabis instead. "The study concluded that 71 percent of the patients who received cannabis reported no vomiting and only moderate nausea following chemotherapy treatment."

In today's cannabis culture, there are a wide variety of methods for consuming cannabis, but not all are recommended for patients suffering nausea and vomiting. Edibles are not the preferred method for combatting these symptoms because of the time it takes to take effect. Vaporization is great because of the rapid onset of relief and it is a healthier option than smoking, but for those with respiratory illnesses as well, this method is not ideal. Luckily, for those who need quick relief but do not want to inhale their medication, tinctures or pills are available. 

Visit Whaxy for a deeper look at cannabis and nausea and vomiting, including anecdotal testimonies, an array of clinical studies, and a list of recommended strains for combatting these symptoms.  

CBDv: Cannabidivarin Cannabinoid Profile

The cannabis plant is extremely complex, and within the layers of the plant are microscopic molecules called cannabinoids. There are more than 111 different types of cannabinoids. This Whaxy cannabinoid profile will discuss the porperties of Cannabidivarin (CBDv).

CBDv is a non-psychoactive cannabinoid like the cannabinoid CBD, which is known for its ability to treat neurological disorders. The cannabinoid has not been widely studied in the U.S, but research exists from the studies conducted in Canada, England and Italy. The results of those studies suggest CBDv is a potential treatment option for seizure disorders like epilepsy, and the nausea and vomiting that sometimes result from the use of pharmaceutical medications. CBDv is most common in strains that have very little THC that will not have a strong psychoactive effect. 

Do you think CBDv could be helpful in treating your symptoms? Read this Whaxy profile for more information on the cannabinoid and for a list of strains that are high in CBDv: http://bit.ly/1K9q56g