Marijuana's Effects On Your Bones

Photo Credit: Civilized

Photo Credit: Civilized

A cannabinoid found in marijuana, cannabidiol (CBD), may boost bone health by strengthening bones and supporting bone fracture healing. In a study from Israel, rats with mild fractures in their femurs were separated into groups that either healed naturally, received CBD as a therapy, or received both CBD and THC therapies. Both groups that received CBD healed faster than those who healed naturally. THC did not seem to influence the healing process. Researcher Yankel Gabet explains, "We found that CBD alone makes bones stronger during healing, enhancing the maturation of the collagenous matrix, which provides the basis for new mineralization of bone tissue… After being treated with CBD, the healed bone will be harder to break in the future."

This information has been provided by Civilized and approved by our Chief Medical Officer.

Medical Marijuana and the Acceleration of Bone Healing

Photo Credit: Marijuana Health Wellness

Photo Credit: Marijuana Health Wellness

A new study from Tel Aviv University and published in the Journal of Bone and Mineral Research suggests CBD-based medicines accelerate the healing of broken bones. In the study from TVU's Bone Research Laboratory, researchers led by Dr. Yankel Gabet administered CBD to rats, whose bones now only healed more rapidly, but also became stronger as an end result. In previous studies, CBD was already found to be a safe medication. Gabet said to the Times of Israel, "...we should continue this line of study in clinical trials to assess its usefulness in improving human fracture healing."

These results are encouraging, but they leave much to be desired when it comes to medical marijuana research. We ask you to journal daily for whatever symptom you're treating, so that we can use your anonymous information to contribute to a better understanding of marijuana in the  medical community. With your help, we can learn more about the safety and efficacy surrounding medical cannabis. This information has been provided in part by Marijuana Health and Wellness and approved by our Chief Medical Officer. 

Cannabidiol and Bone Fracture Healing: Promising Data Published on Medical Marijuana

Photo: Marijuana Investor News

Photo: Marijuana Investor News

Evidence continues to mount in support of cannabidiol (CBD) in the treatment of bone fracture healing thanks to 18 scientists from Israel and Sweden. Research has shown CBD can "enhance fracture healing and stimulate Lysyl Hydroxylase (a highly abundant enzyme involved in bone healing) activity in osteoblasts (bone building cells)." Research has been performed on the cannabinoid's effect on bone healing, but never with such a large group of scientists. Marijuana Investor News discusses this new study further. 

The study consisted of three experiments; one that injected THC or CBD into rats with fractured femurs, one that analyzed the effects of an equal part CBD/THC mixture on a fracture callus, and one that looked at the effects of THC and CBD on the expression of osteoblast enzyme lysyl hydroxylase that catalyzes collagen crosslinking.

The first experiment concluded "stimulation of endocannabinoid receptors of bone cells with cannabis ligands improved the rate of bone healing... [and] CBD significantly enhanced the mechanical properties and strength of bone after eight weeks." The second experiment found THC increased the maximal force and stiffness of bone a little more than CBD. Lastly, the third experiment discovered CBD increased mRNA levels of the lysyl hydroxylase gene. "This data is probably the most significant finding in cannabis research to date because it gave scientists insight into the genetic impact of cannabis on the body. Everything starts with genetics and this concrete data gives us a deeper insight into how cannabis influences the body's physiology." 

For a more detailed look at these findings, read guest contributor Fabian Hernandez's piece on MJINews. 

Study: CBD Administration Enhances Skeletal Healing

A study from the Hebrew University Bone Laboratory revealed the administration of cannabidiol (CBD) leads to improved bone fracture healing. In the study, investigators administered CBD to rats with mid-femoral fractures, and reported, “CBD markedly enhanced the biomechanical properties of the healing femora after 8 weeks.” CBD is considered a safe agent, so we hope this research will advance into an investigation of bone fracture healing in humans. 

http://bit.ly/1NblsIZ