What Are The Medical Benefits of CBD? - Part 2

Photo Credit: NeedPix (https://bit.ly/2XK0i4H)

Photo Credit: NeedPix (https://bit.ly/2XK0i4H)

In today’s post, we’ll continue our discussion of which conditions could benefit from CBD treatment.

We’ll begin with Alzheimer’s disease, which scientists believe CBD could treat or even prevent its onset. A 2013 study found CBD prevented the development of amyloid beta plaques, while another study found CBD promoted the growth of new brain cells that were lost to damage caused by the condition, and that it improved symptoms associated with cognitive deficits. The topical application of CBD may treat acne, and studies have found it can reduce inflammation and the production of sebum oil, as well as halt the development of acne. CBD can also help with psoriasis, and studies have found the cannabinoid can prevent the spread of cells that cause the condition’s patches. CBD may also help cancer patients, not only by reducing the nausea and vomiting associated with chemotherapy, but also by preventing the spread of cancer cells and causing cancer cell death. Studies have also found CBD slows the formation of blood vessels within tumors, thereby blocking nutrients from entering the tumor and slowing its growth.

CBD has also been earning a name lately for treating pain and reducing the need for the harmful opiate medications that are traditionally used. Studies have found CBD reduces inflammation and the sensory perception and emotional effects of pain. Research suggests CBD is more effective at treating long-term neuropathic pain than short-term pain. CBD may protect against heart disease, and studies have found the cannabinoid protects cardiac cells when blood supply to the heart is blocked, stops heart arrhythmia, and reduces cardiac damage when oxygen is block. CBD also reduces heart disease from diabetes by reducing inflammation, oxidative stress, scarring, and cell death. The topical application of CBD can target localized areas of pain caused by arthritis. Studies have found CBD blocks pain and prevents nerve damage from osteoarthritis, as well as uses anti-inflammatory and immunosuppressive effects to blog the condition’s progression. Some studies have found CBD may be able to stabilize mood, something that could be helpful for those suffering from Bipolar Disorder. That said, CBD was only effective during depressive stages, and not during manic phases.

That’s not all! Stay tuned for tomorrow’s post to learn more about which conditions CBD could help. This information has been provided by Leaf Science and approved by our Chief Medical Officer.

What Are The Medical Benefits of Marijuana? - Part 4.

Photo Credits: Leaf Science

Photo Credits: Leaf Science

After having discussed so many way marijuana can be applicable in medicinal instances, it’s time we conclude our discussion.

Many people may be aware of short spurts of anxiety following marijuana use, but what they don’t know is that marijuana could actually improve anxiety long-term. The non-psychoactive cannabinoid CBD, specifically, has been deemed as effective as approved anti-anxiety medications. Studies have found marijuana may manage the overactive immune system associated with lupus. This, as well as marijuana’s inherent anti-inflammatory properties, can help alleviate symptoms of pain and inflammation that coincide with the condition. Many patients have experienced relief from the pain and inflammation associated with arthritis, however these results have proven inconsistent in what studies exist, and while the medication is well tolerated, some patients did not experience any relief at all. More research is desired.

Cannabinoids also help stimulate bone formation, prevent bone resorption, and prevent loss of bone mass making marijuana a potentially powerful player in therapy for osteoporosis. By reducing the side effects associated with Hepatitis C treatment regimens, marijuana use encourages patients to complete their treatments and helps lead patients to remission. Its stimulation of certain receptors may also improve treatment outcomes. Marijuana may also help those who suffer from severe headaches like migraines by reducing their frequency and severity. Lastly, researchers have discovered lower prevalence of diabetes and non-alcoholic fatty liver disease in marijuana users. Marijuana users, in general, have lower insulin levels, smaller waists, are less likely to be obese.

This concludes our post on the many ways marijuana can treat a myriad of symptoms. Thanks for following along for the discussion! This information has been provided by Leaf Science and approved by our Chief Medical Officer.

What Are The Medical Benefits of Marijuana? - Part 1.

Photo Credits: Leaf Science

Photo Credits: Leaf Science

Medical marijuana is now being touted for having a wide range of medicinal benefits that allow it to provide therapeutic relief for many different conditions. In this four part series, we will take an in depth look at many of the medical conditions it is capable of treating.

One of the most commonly cited and widely approved conditions for marijuana use is chronic pain. Marijuana is known for its analgesic and anti-inflammatory properties, making it effective in reducing pain and providing relief for the conditions that cause it, like arthritis, cancer, multiple sclerosis, and migraines. Medical marijuana is also used for treating glaucoma, a condition that affects sight and can damage the optic nerve due to increased pressure in the eye. Studies have found marijuana decreases intraocular eye pressure by 25-30%, and scientists believe its neuroprotective properties could prevent the optic nerve from getting damaged. Medical marijuana may also help those suffering from liver disease. The cannabinoid CBD can prevent liver fibrosis, while THC may be able to help improve the symptoms associated with cholestatic liver disease.

Marijuana is also promoted as a hero for cancer patients, mainly for its ability to reduce the nausea and vomiting accompanying chemotherapy treatments. Even more exciting, in rodent models, THC and cannabinoids have been found to induce apoptosis in cancer cells without affecting healthy cells. In other rodent models, THC reduced tumor size. Contrary to what has long been claimed by prohibitionists about cannabis’ relationship to schizophrenia, studies have found non-psychoactive compounds like CBD may actually benefit psychosis. CBD is antipsychotic and generally well tolerated. But be careful, as THC may actually exacerbate symptoms. Lastly, recent clinical trials have found medical marijuana help those with multiple sclerosis by combatting muscle spasticity, reducing pain, and improving sleep quality.

That concludes today’s post on the medical benefits of medical marijuana, but there’s still so much more to discuss! Tune into the following post where we will look at more conditions where medical marijuana’s usage is applicable. This information has been provided by Leaf Science and approved by our Chief Medical Officer.

3 Benefits of THC

Photo Credit: MassRoots

Photo Credit: MassRoots

While THC is known for producing a psychoactive "high" for recreational users, medical marijuana patients and researchers recognize THC also has medicinal properties to it. THC is a cannabinoid that occurs naturally in the cannabis plant, and that is able to connect to receptors throughout the endocannabinoid system and in the brain and immune system. THC is already known for its ability to increase appetite, but this can be especially effective for treating nausea and vomiting and stimulating appetite in patients suffering from HIV or cancer. It has also effectively increased appetite in patient suffering from illnesses like anorexia or Alzheimer's. This helps users maintain a stable body mass.

Recently, CBD has been gaining a lot of attention for its efficacy in pain management, which could have a beneficial impact on the opioid epidemic. What isn't as well known, however, is that THC also has analgesic properties. Studies have found THC effectively treats pain associated with rheumatoid arthritis, cancer, headaches, menstrual pain, chronic bowel inflammation, and nerve damage. A study from the University of Michigan involving 185 patients found medical cannabis users experienced a 45% increase in their quality of life. Lastly, it is thought THC may help those who suffer from anxiety or depression. THC has fewer side effects than the commonly prescribed anti-depressant medications, and it can increase serotonin levels which helps relieve depression. 

This information has been brought to you by MassRoots and approved by our Chief Medical Officer. 

 

Terpene Series: Caryophyllene

Photo Credit: The Leaf Online

Photo Credit: The Leaf Online

Beta-caryophyllene, a peppery, woody, and spicy smelling terpene, is the only terpene known to interact with the endocannabinoid system. The terpene binds with CB2 receptors, acts as a functional CB2 agonist, and functions as a non-psychoactive ligand. Research suggests the terpene may be promising for cancer treatment and serves as a macrocyclic anti-inflammatory component in cannabis.

One study found beta-caryophyllene, in combination with cannabinoids like CBD, provided chronic pain relief without adverse side effects when administered orally. Another found the terpene, through a CB2 receptor dependent pathway, could prevent nephrotoxicity caused by chemotherapy drugs. Another study isolated the chemical compounds of black pepper, of which beta-caryophyllene is a large constituent, and found black pepper oil contained antioxidant, anti-inflammatory, and antinociceptive properties. This suggests cannabis strains that also contain high levels of beta-caryophyllene might be able to treat issues like arthritis and neuropathic pain.

This information was brought to you by Medical Jane and approved by our Chief Medical Officer. 

Health Benefits of Cannabis

Photo Credit: iStock.com/LattaPictures

Photo Credit: iStock.com/LattaPictures

By now it's no surprise that cannabis can offer a wide range of medicinal benefits for a wide variety of illnesses and symptoms. Here are a few ways cannabis can help patients improve their health:

Cannabis has the ability to attack cancer cells. According to a study published in 2014 in the Molecular Cancer Therapies medical journal, researchers from St. George's University of London found marijuana killed certain cancer cells and reduced the size of others in animal trials. They found whole-plant extracts shrank some of the most serious types of brain tumors. Cannabis can also tackle arthritic pain, and Canada has been using it to treat arthritis since 2001. Those who suffer from lupus can benefit from cannabis' ability to manage chronic pain and reduce swelling. Contrary to the beliefs of many, cannabis is not as harmful on the lungs as previously thought. In fact, one study published in the Journal of the American Medical Association found moderate amounts of cannabis consumption might actually improve lung capacity. Taking either CBD or THC before falling asleep can help improve one's overall sleep. Lastly, findings published in the American Journal of Medicine suggest cannabis can actually help you lose weight. 

This information has been adapted from Black Enterprise and approved by our Chief Medical Officer.

Medical Marijuana for the Treatment of Arthritis

Photo Credit: Medical Marijuana Inc. 

Photo Credit: Medical Marijuana Inc. 

There are over 100 different types of arthritis, but they all cause pain and swelling of the joints. Those who suffer from arthritis also experience stiffness and a decreased range of motion. When symptoms become severe enough, they interfere greatly with one's daily activities. The most common forms of arthritis include osteoarthritis, rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, infections arthritis, and gout. Current treatments involve medications that relieve pain and swelling, physical therapy, and surgery, but research suggests cannabis should be added to the list due to its anti-arthritic effects and ability to manage pain and inflammation.

Preclinical trials reveal cannabis can reduce the damage arthritis causes. In one animal trial, CBD blocked the progression of arthritis. Researchers found CBD projects joints from damage and offers potent anti-arthritic effects. More recently, researchers found cannabinoids prevented osteoarthritis from progressing by inhibiting protease, which is associated with degradation of joint cartilage. Additionally, studies on mice with osteoarthritis have shown synthetic cannabinoids offer anti-inflammatory and immunosuppressive properties, thereby reducing joint damage. One study found cannabis-based medicine reduced pain during joint movement, reduced pain at rest, and improved quality of sleep for patients suffering rheumatoid arthritis. Lastly, studies have shown both CBD and THC are capable of managing the pain and inflammation associated with arthritis.

This information has been brought to you by Medical Marijuana Inc. and approved by our Chief Medical Officer. 

Linalool Cannabis Terpene

Photo Credit: Whaxy

Photo Credit: Whaxy

Medical marijuana patients are most likely familiar with the cannabinoids of marijuana that are responsible for providing a lot of the medical relief the plant is accredited with, but not everyone knows so much about terpenes which are also responsible for providing medicinal benefits. There are over 20,000 terpenes in nature, 200 of which exist in cannabis. One of these terpenes is Linalool.

Linalool may not be a major terpene, but studies have found it can alleviate a variety of symptoms, including pain, depression, seizures, inflammation, and even insomnia. The terpene is considered an analgesic, making it a popular method for treating conditions like multiple sclerosis, dystonia, arthritis, post-operative pain, and chronic pain. That anti-inflammatory properties of linalool make it an effective molecule for combatting inflammation-based diseases like Crohn's, arthritis, asthma, Alzheimer's, fibromyalgia, dermatitis, IBS, lupus, and Parkinson's disease. The terpene also acts like an antidepressant, an anti-convulsant for those who suffer from seizures, and a sedative or sleep aid. 

Linalool is promising as a key player for providing therapeutic relief, but more research is left to be desired in order to understand exactly how the terpene is able to do so and how it interacts with other terpenes and cannabinoids to provide optimal relief. This information has been provided by Whaxy and approved by our Chief Medical Officer. 

Beta-Caryophyllene (BCP)

Photo Credit: Whaxy

Photo Credit: Whaxy

It seems the amount of information we can learn about the tiny cannabinoids and terpenes is endless. This may be because there are tens of thousands of these molecules found in nature, and 200 different terpenes and 111 different cannabinoids are present in the cannabis plant. Whaxy does an excellent job analyzing cannabinoids and terpenes, and today's feature will discuss the Beta-caryophyllene (BCP) terpene. 

Beta-caryophyllene doesn't exist in the cannabis plant alone; it can also be found in cloves, oregano, hops, rosemary, and black pepper. BCP targets the CB2 receptors in the body, meaning it does not contribute to the euphoric high commonly associated with cannabis. Whaxy says, "BCP is an effective way to medicate while avoiding any alteration in perception or motor skills. It can be used to treat several inflammatory disorders, including arthritis and multiple sclerosis... BCP has also been show to fight cancer, reduce anxiety and depression, and has even been found to be gastroproductive - meaning it can be used to treat ulcers." BCP works best alongside other terpenes and cannabinoids in what is called "the entourage effect."

A study published in 2014 in the journal Pharmacology Biochemistry and Behavior suggests BCP could be effective in combatting alcoholism. In the study, BCP was injected into animals, resulting in decreased ethanol consumption and preference. Because BCP is not exclusive to the cannabis plant, it is legal and abundant. That being said, BCP is thought to be more effective supplementing other cannabinoids and terpenes found within the cannabis plant, and we will not know its full potential until marijuana is reclassified and studied further. 

Read in detail about Beta-caryophyllene on Whaxy

Cannabis Topicals: Getting Under Your Skin

When people think about medicating with cannabis, they think about the most common methods of inhalation or ingestion, but there are a wide range of methods available. Many don't realize that cannabis is lipophilic and can be absorbed through the skin, so they don't realize how effective cannabis topicals are as a path to quick relief and a way to target localized areas. 

Whaxy discusses the ailments that would benefit from the use of topicals, "from generalized conditions such as inflammation, tension, and soreness to specific ailments like eczema, dermatitis, puritis (itching), and psoriasis." However, the most significant use for topicals is in the treatment of arthritis, the number one cause of disability in the U.S. If the topical contains the right combination of cannabinoids, it can relieve arthritic symptoms by acting as an anti-inflammatory in specifically targeted areas.

Topicals are also an effective treatment option for those who want to treat their conditions without feeling a euphoric high. Topicals interact with the CB2 receptors in the skin which do not allow THC to permeate the bloodstream and flow to the brain. Because of this, topicals are well-suited for children and those who would like to avoid the high or negative side effects sometimes associated with marijuana.

Whaxy suggests topicals could be useful in household items like patches, salves, and lotions that could treat everyday annoyances like bug bites, muscle aches, or headaches. You can read Whaxy's full analysis here

Cannabis Offers Hope and Comfort to Arthritis Patients

Photo Credit: BlazeNow

Photo Credit: BlazeNow

Arthritis affects over 50 million adults in the United States, and the two forms (osteoarthritis and rheumatoid arthritis) which affect the joints cause pain, swelling, and hinder movement. Now, evidence is mounting in support of the effect certain cannabinoids' have on reducing pain and inflammation, and promoting bone health, all of which would benefit the many sufferers of arthritis. The use of cannabis to treat arthritic pain and inflammation is significant because the current anti-inflammatory or pain-relieving medications available to patients have the potential to damage the liver. This is not the case with medical marijuana which bypasses the liver.

The Americans for Safe Access report "Arthritis and Medical Cannabis" discusses how marijuana is more than just a tool for symptom management. "Cannabis has also been shown to have powerful immune-modulation and anti-inflammatory properties suggesting that it can play a role not just in symptom management but treatment of arthritis." 

For more information on cannabis for arthritis and the research that supports its use, read this article from BlazeNow. 

10 diseases where medical marijuana could have impact

10 diseases where medical marijuana could have impact

Marijuana is one of the tightest controlled substances under federal law, but it's gaining popularity among patients as a medication for a variety of illnesses. Many Drs. have also changed their tune in support of the drug, including Dr. Sue Sisley, Dr. Sanjay Gupta, and Dr. Mehmet Oz. This CNN report highlights some of the illnesses medical marijuana could potentially treat, including PTSD, AIDS and HIV, Alzheimer's, Arthritis, Asthma, Cancer, Chronic Pain, Crohn's Disease, Epilepsy and Seizure disorders, Glaucoma, and Multiple Sclerosis. http://cnn.it/1Nimp33

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Oregon medical marijuana patient says edibles more effective than smoking for pain relief

Figuring out the best method for targeting specific symptoms with medical cannabis can be extremely difficult. This is especially hard for patients who are just starting out and have never experimented with the medication before. Choosing a method really depends on an individual's personal preference, but when you don't know where to begin it can be helpful to look to more experienced users for guidance. At CannaBest medical, we find this information very helpful, which is why our tool displays consolidated data in the form of simple graphs that show our users the most popular methods for treating specific conditions. For more detailed information about why people prefer specific treatment options, it can be helpful to look at anecdotal references. Here is an article with an in depth look at a patient in Oregon who believes using medical marijuana edibles is the most effective method for treating the pain associated with her severe Arthritis: http://bit.ly/1RtFFLe

To learn more about CannaBest Medical and its medical marijuana dosing guidance tool, visit www.cannabestmedical.com

The Use of Cannabis to Provide Symptom Relief

Information about using cannabis to provide symptom relief is gaining traction as legalization spreads across the U.S. Some conditions are widely known to be treatable with medical marijuana, but did you know it can also help fight Alzheimer's, Premenstrual Syndrome (PMS), Arthritis, Neuropathic Pain, and Acne? For a more in depth look at each of these conditions, check out Whaxy's analysis. http://bit.ly/1Rtqdz1