What Are The Medical Benefits of Marijuana? - Part 3.

Photo Credits: Leaf Science

Photo Credits: Leaf Science

In the last post, we continued to look at the conditions where medical marijuana is effective. It’s not done yet! We’ll continue the discussion below.

While the relationship between marijuana and heart disease is complicated, and cannabis can actually exacerbate symptoms in some users by increasing heart rate and blood pressure, scientists have found low doses of THC can reduce damage from heart attacks, and CBD can be used as a treatment for cardiovascular disease. Cannabis may also reduce the severity and lessen the impact of a stroke. Although most studies thus far have been animal studies, researchers believe medical cannabis may help treat the symptoms of Huntington’s disease, and one human study found synthetic THC improved motor-related symptoms of the disorder. Animal studies have found cannabis may slow the progression of Amyotrophic lateral sclerosis, and many properties of cannabis could help reduce pain, relax muscles, reduce saliva, stimulate appetite, and induce sleep. Synthetic cannabinoids also improved pain symptoms in fibromyalgia patients, and one survey found patients actually preferred cannabis to any approved pharmaceutical medication.

New support is starting to accumulate for the use of marijuana for Alzheimer’s disease. Marijuana may be able to do so by reducing inflammation and the formation of plaques. Marijuana has been found to alleviate tics and be well tolerated in patients with Tourette’s syndrome. Cannabis topicals are now offered as effective treatments for varying skin disorders, and its anti-inflammatory and anti-itching properties make it effective for the treatment of acne, dermatitis, and psoriasis. Marijuana may also help those who suffer from sleep disorders like insomnia and sleep apnea fall asleep quicker and improve breathing during sleep. Lastly, and probably most well known, is medical marijuana’s ability to treat epilepsy. Specifically, the cannabinoid CBD is well-tolerated and effective in reducing the frequency and severity of seizures.

There are even many more conditions to talk about regarding medical marijuana treatment. Keep reading as we conclude our discussion in the next post! This information has been provided by Leaf Science and approved by our Chief Medical Officer.

Is CBD the Next Big Thing for Acne?

Photo Credit: Leafly

Photo Credit: Leafly

Botanix Pharmaceuticals Ltd., has recently completed phase 1 of a clinical trial involving the use of synthetic cannabidiol (CBD) for the treatment of acne. The preliminary trial took place in Australia, where twenty participants applied the synthetic cannabinoid, which is called BTX 1503, topically for a month. Researchers looked towards the safety, tolerability, and phaymacokinetics (which refers to the amount of drug that remains detectable in the bloodstream after use). The trial was completed within 12 months and was deemed a huge success, with the company stating, “Top line data demonstrates that BTX 1503 has an excellent safety profile, with little to no skin irritation, and no severe adverse events were recorded.”

Previously, a study from 2014 published in the Journal of Clinical Investigation found CBD inhibited lipogenic action and the production of sebocytes in biopsies of human scalp and arm skin. Both of those processes contribute to the development of acne. Additionally, CBD produced anti-inflammatory effects.

This information has been provided by Leafly and approved by our Chief Medical Officer.



Is Cannabis Beneficial for Acne?

Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

Research has found cannabinoids can be beneficial in the treatment of a wide variety of skin conditions, including psoriasis, eczema, and dermatitis. While there is little information surrounding the use of cannabis for targeting acne, what data we have suggests it may indeed offer an effective alternative treatment option. Sebaceous glands contain cannabinoid receptors, suggesting they may be modulated through the use of cannabinoids and their interactions with the endocannabinoid system. CBD inhibits lipid production throughout skin cells, which allows it to regulate the secretions of oils in the skin. One clinical trial investigating CBD facial serum found 100% of participants reported an improvement in skin appearance over the course of two weeks. Similarly, hemp oil significantly reduced sebum secretion and was well tolerated by participants who used it over the course of 12 weeks. CBD's anti-inflammatory properties could allow it to reduce the swelling and redness caused by acne. Lastly, the antibacterial properties of various cannabinoids could in turn prevent acne. 

This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer. 

10 Little-Known Uses for CBD - Pt. 1

Photo Credit: High Times Magazine

Photo Credit: High Times Magazine

CBD is constantly hailed as a miracle cannabinoid as research comes out pointing to its medicinal benefits. Here are some medicinal uses you may or may not know about CBD. 

One study found CBD may be able to combat cigarette addiction. In the double-blind study, 24 smokers received either an inhaler of CBD or placebo, and were asked to inhale every time they felt the urge to smoke a cigarette. Those who received CBD experienced a 40% drop in cigarette intake and no increase in nicotine cravings, while those who received placebo experienced no change. Another study from the Journal of Clinical Investigation and the National Institute of Health found cannabis-derived CBD on human sebaceous glands is an effective sebostatic and anti-inflammatory agent that inhibits lipid synthesis, thereby treating acne.

Another study found CBD prevented the development of diabetes in non-obese diabetic mice through the prevention of IL-12 production by splenocytes, a cytokine that plays a role in human autoimmune diseases. In 2011, a study looked at CBD for the treatment of fibromyalgia. Out of 56 patients, half used CBD while the other half used traditional treatment regimens. Those who used cannabis witnessed a reduction in symptoms and pain, while those who used continued using traditional methods saw little improvement. Lastly, a study from the Journal of Neuroscience in 2007 found CBD can halt the proteins prions, something that would be beneficial in preventing neurodegenerative diseases like Creutzfeldt-Jakob disease and mad cow disease. 

This information has been provided by High Times Magazine. Stay tuned for tomorrow's post to discover more about CBD's uses. This information has been approved by our Chief medical officer. 

The Use of Cannabis to Provide Symptom Relief

Information about using cannabis to provide symptom relief is gaining traction as legalization spreads across the U.S. Some conditions are widely known to be treatable with medical marijuana, but did you know it can also help fight Alzheimer's, Premenstrual Syndrome (PMS), Arthritis, Neuropathic Pain, and Acne? For a more in depth look at each of these conditions, check out Whaxy's analysis. http://bit.ly/1Rtqdz1