Areas of the brain responsible for controlling memory are regulated by the endocnannabinoid system, leading researchers to hypothesize cannabinoids found in cannabis may be able to help those suffering from Alzheimer’s disease. As Alzheimer’s develops, beta-amyloid plaques block and disrupt the endocannabinoid system, which could be responsible for producing the early symptoms of memory impairments. Because cannabis is known to interact with this system and resolve endocannabinoid deficiencies, it could resolve these issues. Cannabinoids not only interact with this system, but also contain neuroprotective and anti-inflammatory effects that could benefit those with the condition. Studies have found cannabinoids protect brain cells from damage and prevent disruptions in cognition in animal models of Alzheimer’s. Cannabis’ anti-inflammatory properties could prevent inflammation from damaging neurons and contributing to neurodegeneration in Alzheimer’s patients, and one study from 2009 confirmed cannabinoids helped to regulate inflammation in the brain.
This information has been provided by Leaf Science and approved by our Chief Medical Officer. In our next post, we will discuss how specific cannabinoids like THC and CBD could be useful in treating the condition.