Researchers from Indiana University have found equal parts THC and CBD can prevent memory impairment and prevent increased anxiety in mice. The new study has found that higher amounts of CBD could buffer against potentially harmful long-term effects associated with smoking marijuana. In the study, researchers injected mice everyday for three weeks with doses of either THC or CBD, THC and CBD, or neither cannabinoid. When only given THC, mice experienced increased anxiety and memory impairment. When they received equal parts THC and CBD, however, they did not exhibit the same side effects. Lead author Dr. Ken Mackie explains this information "suggests that strains of cannabis with similar levels of CBD and THC would pose significantly less long-term risk due to CBD's protective effect against THC.”
The adolescent and adult mice were divided into five groups, those who received THC only, those who received CBD only, those who received equal parts of both cannabinoids, those who received placebo, and those who received no treatment. Researchers observed immediate reactions after testing, and then tested them again six weeks later. Adolescent mice who received only THC exhibited negative symptoms six weeks later, while adult mice did not, suggesting teenagers may experience side effects that differ from adults. Equal doses of THC and CBD did not affect neither adolescent nor adult mice.
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