Tetrahydrocannabinolic acid (THCA): The Raw Cannabinoid For Pain - Part 2

Photo Credit: MassRoots

Photo Credit: MassRoots

In our previous post, we briefly introduced the raw and acidic form of THC, known as tetrahydrocannabinolic acid (THCA). In this post, we will continue our discussion by taking a closer look at all the cannabinoid has to offer. 

THCA may be able to reduce nausea and vomiting, and in a study published in the British Journal of Pharmacology, THCA reduced nausea and vomiting without intoxicating rodents and shrews who showed nausea behaviors and who received a substance that induced vomiting. Another study found THCA blocks the same enzymes that NSAIDS target from manufacturing pro-inflammatory compounds, suggesting the compound contains anti-inflammatory properties. Another study from 2012 found THCA reduced the progression of Parkinson's Disease in experimental models. In the experiment, THCA reduced damage to neurons from positively charged neurotoxins. 

A study from 2008 suggests THC and THCA both engaged the cell receptor TRPA1, a receptor that is currently under the gaze of many pain researchers for its role in inflammatory, neuropathic, and migraine pain. Lastly, according to research published in 2013, THCA may contain anti-cancer and anti-proliferative effects. The study involved laboratory models of prostate cancer, and although its effects were not as significant as the effects of CBD, there is still reason to investigate THCA further. 

This concludes our discussion of THCA. This information has been provided by MassRoots and approved by our Chief Medical Officer.