The Unknown Science Behind the “Entourage Effect” of Chemicals in Marijuana

 Photo Credit: Merry Jane

Photo Credit: Merry Jane

Medical marijuana is known to produce symptom relief for a myriad of conditions and illnesses, but these effects are largely dependent on the chemical makeup of the particular strain chosen. This is because the cannabinoids and terpenes found in cannabis interact with each other in what has been deemed the entourage, and variations in the amount of these chemicals will produce a different effect. Many researchers believe when these compounds work together, they can enhance the therapeutic properties of cannabis and buffer against the psychoactive effects.

That said, the entourage effect is still relatively unknown due to federal scheduling that prevents significant marijuana research. Other researchers like neurobiologist and cannabis researcher Margaret Haney isn't fully convinced, and says more information is needed as to whether or not the entourage effect really exists. She explains, “The lay public has really taken on the notion of the entourage effect, but there’s not a lot of data. The cannabis field can say anything and it does. I’m not against marijuana. I want to study it carefully. We know it can affect pain and appetite but the large majority of what’s being said is driven by anecdotal marketing. These guys are really trying to make money.”

This information has been provided by Merry Jane and approved by our Chief Medical Officer.