What is the Endocannabinoid System?

Photo Credit: MassRoots

Photo Credit: MassRoots

Medical cannabis appears to have a myriad of therapeutic effects, and the reason it's able to provide such relief is due to its ability to interact with the endocannabinoid system (ECS). The ECS is made up of cell receptors, enzymes, and endogenous ligands or binding molecules, that are responsible keeping the body stable and in a state of homeostasis. The body naturally produces endocannabinoids, and when the body experiences a deficiency in endocannabinoids it can cause the body to become out of balance, uncomfortable, and even ill.

This is where cannabis can provide its relief. Cannabis consists of hundreds of cannabinoids which can bind with CB1 and CB2 receptors in the endocannabinoid system, filling the void of an endocannabinoid deficiency, and thereby returning the body to a state of homeostasis. The cannabinoid THC can bind with CB1 receptors, which exist in the brain, muscles, hear, lungs, and more. CB2 receptors are found in the liver, gut, and muscles, and work closely with the body's immune system. As opposed to binding with receptors, CBD focuses no optimizing enzymes like FAAH and MAGL so that they do not break down anandamide and 2-AG, which thereby allows the body's endocannabinoids to increase. 

This information has been provided by MassRoots and approved by our Chief Medical Officer.