The use of medical marijuana in the treatment of depression is controversial, but some studies do suggest the medication could be beneficial in its treatment and the treatment of its associated symptoms like fatigue, pain, stress, and anxiety. One study from the University of Buffalo suggests marijuana may be able to positively alter chronic stress, of which depression is linked to. Stress chips away at endocannabinoids in the brain, so it is suggested cannabis may be able to restore these chemical compounds in order to return to homeostasis and create a balanced mood. The study was originally conducted on animals, but the study's authors have since continued exploring these results for verification.
The findings from another study from McGill University in 2007 creates a clear discovery of how marijuana mimics the effects of endocannabinoids, and how those endocannabinoids directly influence serotonin, which is a vital chemical in the fight against depression. The authors determined marijuana could benefit depression, as long as patients don't consume too high of a dose.
This information has been provided by the Medicinal Marijuana Association and approved by our Chief Medical Officer.