The fact that THC binds to and activates the CB1 receptor in the endocannabinoid system is nothing new, but now scientists better understand this process. Research from the iHuman Institute of Shanghai Tech University that was published in the journal Cell has led scientists to discover that the receptor is a three dimensional crystal structure. Knowing the structure of the receptor allows scientists to discover insight into how different molecules can bind to it, which could be crucial in understanding how cannabinoids can target receptors to provide symptom relief. Co-author of the study, Raymond Stevens, says, "What is important is to understand how different molecules bind to the receptor, how they control the receptor function, and how this can affect different people."
This discovery could provide important information when comparing the different ways synthetic and natural cannabinoids interact with the receptors, as natural cannabinoids provide symptom relief, and synthetic cannabinoids can have adverse and even deadly side effects.
This information has been provided by Civilized and approved by our Chief Medical Officer.