Influencing the Endocannabinoid System Beneficial for Parkinson's Disease

 Photo Credit: Medical Marijuana Inc.

Photo Credit: Medical Marijuana Inc.

A recent review published in Cannabis and Cannabinoid Research suggests interaction with the endocannabinoid system could help manage symptoms associated with Parkinson's disease. Researchers from the Department of Systems Medicine at Rome's Tor Vergata University looked at preclinical and clinical studies on cannabinoid therapies and Parkinson's disease. They found that activating cannabinoid receptors successfully modulated the release of dopamine, and improved motor impairment. Two survey's involving patients diagnosed with Parkinson's disease found smoking marijuana reduced tremor, rigidity, bradykinesia, pain, and improved sleep. CBD was also found to have helped reduce psychosis related to Parkinson's disease. Additionally, a study conducted at the Tel Aviv University and Rabin Medical Center found cannabis reduced motor symptoms and pain in Parkinson's disease patients. 

While this information is positive, more research is left to be desired due to small sample sizes, expectancy biases, and the absence of standardized outcomes. This information has been provided by Medical Marijuana Inc. and approved by our Chief Medical Officer.