Recent data published in the journal Epilepsy & Behavior suggests whole-plant cannabis extracts that contain high levels of CBD are associated with reduced seizure frequency in patients with refractory epilepsy. Researchers reviewed the clinical records of 272 patients who were taking whole-plant CBD extracts and found 86% of them observed clinical benefit, or a reduction in seizure frequency, while 10% experienced complete clinical response. The other patients either felt no relief or experienced an exacerbation of seizures during therapy. Patients also reported improved mood, better sleep quality, and increased appetite. Authors concluded, “The cannabinoids’ novel mechanisms of action are an attractive consideration for possible seizure control... In patients with refractory epilepsy that have a low likelihood of responding to a subsequent AED (anti-epileptic drug), a trial of artisanal cannabis formulas may be indicated.”
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