Cannabidiol (CBD): Medical Uses, Effects & Safety - Pt. 2

 Photo Credit: Leaf Science

Photo Credit: Leaf Science

In our previous post, we gave a brief overview of CBD and its interaction with the body. In today's post, we will take a deeper look at how CBD affects different symptoms and illnesses.

Of all the conditions CBD can treat, it is probably best known for its effects on epilepsy. The FDA has even approved the research of a drug call Epidiolex, which is almost pure CBD oil. In those 12 week trials involving 214 patients with severe and treatment resistant forms of epilepsy, doses between 25 and 50 mg/kg a day lowered seizure frequency by 50%. Another study found CBD can treat anxiety. In 24 patients with social anxiety disorder, patients who received CBD as opposed to placebo measured better in terms of cognitive impairment, discomfort, and alertness before taking a public speaking test than those who were treated with placebo. In fact, those treated with CBD performed as well as cohorts that did not suffer from social anxiety at all. In one study of 29 patients with first-break paranoid schizophrenia, some received either 600 mg CBD or placebo over the course of 14 days, then the treatments were reversed. CBD significantly improved psychotic symptoms.

Another study found 5 patients with dystonic movements disorder improved their symptoms over the course of 6 weeks after they combined 100-600 mg/day CBD with their usual pharmaceuticals. When comparing a group of patients who received a transplant without receiving CBD to a group of 48 patients who received 300 mg/day CBD orally 7 days before receiving a bone marrow transplant to 30 days after treatment, those who received the CBD treatment were less likely to develop graft versus host disease. CBD can also reduce substance dependencies, and in a study of 24 smokers, some received a CBD inhaler in which they were instructed to use whenever they felt a craving to smoke. Over one week, those who received the inhaled reduced the number of cigarettes they smoked by 40%, while those with a placebo inhaler witnessed no change. Lastly, CBD can act as a buffer for THC, so that patients can feel the benefits of THC's therapeutic properties without experiencing the psychoactive side effects.

This information has been provided by Leaf Science and approved by our Chief Medical Officer.