Chronic Inflammatory Demyelinating Polyneuropathy (CIPD) is an acquired rare disorder caused by damage to the myelin sheath that covers nerves. CIPD affects the peripheral nerve system and causes weakness, numbness, pain, tingling, sensory loss, and a loss of reflexes. Current treatment options include corticosteroids, intravenous immune globulins, and plasma exchange, but now studies suggest marijuana could be added alongside these options because of its analgesic and anti-inflammatory properties, and its potential to stall the progression of the disorder.
Cannabis is known for its ability to lower pain levels, and it specifically has demonstrated its ability to do so, even in low doses, in patients with neuropathic and nociceptive pain, even when the pain is refractory to other treatments. Because cannabis suppresses the overactivity of the body's immune system and acts on CB1 and CB2 receptors to regulate the immune system, it may have the ability to reduce the progression of CIPD. THC in particular suppresses both inflammatory responses and the immune system, which can help the body recover from injuries caused by the immune system, like CIDP.
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