There is new research to suggest a lack of balance in the endocannabinoid system, or dysregulation, can result in liver diseases like hepatitis, fibrosis, and cirrhosis. Patients with liver diseases like cirrhosis have CB2 receptors in their liver cells, whereas those without the disease lack these receptors in the area. Because the cannabinoids in cannabis can interact and bind with these receptors in the endocannabinoid system, the plant has the potential to combat the symptoms of these diseases and produce medicinal benefits.
One study published in 2011 in the journal Cell Death and Disease found CBD induced apoptosis in malignant cells in liver fibrosis.The researchers concluded, “Collectively, these results, coupled with the excellent safety and tolerability profile of cannabidiol in humans, strongly suggest that it may have great therapeutic potential…” They added CBD may be an effective treatment for, “…diabetic complications, and perhaps other cardiovascular disorders, by attenuating oxidative/nitrosative stress, inflammation, cell death, and fibrosis.”
With liver diseases like fibrosis afflicting more than 400,000 people in the United States alone, the ability for cannabis to counteract this widespread disease would be a welcomed discovery. This information has been brought to you by Whaxy and approved by our Chief Medical Officer.