Myoclonus is not a disease, but rather a symptom characterized by involuntary contractions of a muscle or a group of muscles. This symptom can severely interfere with someone's daily activities, like eating, talking, or walking. Myoclonus is classified as psychological, essential, epileptic, or symptomatic, the most common being symptomatic myoclonus. Scientists believe myoclonus is linked to the over-excitability of motor pathways that control movement and abnormalities or deficiencies in the reception of certain neurotransmitters.
Many of the medications used to treat epilepsy are also used for the treatment of myoclonus, suggesting that the same anti-epileptic and anti-seizure effects of cannabis could also work for myoclonus. In addition, cannabis' ability to lower neuronal excitability and control muscle contractions could be helpful for those who experience myoclonus. Preclinical trials have shown the cannabinoid CBD provided anticonvulsant effects in mice and rats. As a result of CBD's interaction with the CB1 receptor, neurotransmission is dampened and neuronal excitability is reduced, suggesting CBD could help against myoclonus linked to over excitability. In other diseases that produce tics and tremors, cannabis is able to curtail these involuntary muscle movements. This is because CB1 and CB2 receptors are found in the basal ganglia and cerebellum, areas of the brain in control of muscle movement.
This information was provided by Medical Marijuana Inc. and approved by our Chief Medical Officer.