Lupus is a chronic autoimmune disease that causes inflammation to attack the body's tissues and organs. With autoimmune disorders, the body mistakes healthy tissues for harmful foreign invaders and irregularly responds by producing autoantibodies that lead to inflammation and harm the body's healthy tissues. The skin, kidneys, blood cells, joints, heart, brain, and lungs can all be damaged because of lupus. While the disease is chronic, its symptoms waver between flares and remissions, and they include a facial rash resembling a butterfly, fatigue, fever, joint pain, stiffness, skin lesions, shortness of breath, chest pain, dry eyes, headaches, and figures and toes that turn white or blue. Thanks to cannabis' ability to reduce pain and inflammation, it may help lupus patients to better manage their symptoms.
The cannabinoid THC triggers CB1 and CB2 receptors, stimulating an immunosuppressive response that downregulates the production of cytokines and chemokine while t-regulatory cells are upregulated. One review analysis of research surrounding THC claims it could be a potent treatment modality against inflammatory disorders. In addition, cannabis has analgesic properties that could make it effective in managing the pain associated with lupus.
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