Nausea is a symptom that causes uneasiness and discomfort in the stomach, which leads to the feeling of queasiness and the urge to vomit. Nausea can result from medications, anesthesia, treatments like chemotherapy, or illness like food poisoning, morning sickness, motion sickness, migraines, Crohn's disease, irritable bowel syndromes, and liver or pancreatic cancer. Nausea can affect one's quality of life, and make it difficult to continue with necessary treatment regimens, and when it is left uncontrolled, it can lead to chemical imbalance in the body, mental changes, loss of appetite, malnutrition, dehydration, and a damaged esophagus.
Studies show cannabis both treats nausea and prevents it from occurring. Both THC and CBD effectively regulate nausea and vomiting by activating the endocannabinoid system's CB1 receptor, which allows the body to suppress vomiting. CBD also indirectly activates the sommatodentritic 5-HT(1A) autoreceptors in the brain stem, which contributes to its effectiveness as an anti-nausea agent. Studies have also shown cannabinoids not only provide relief for cancer patients who suffer from post-chemotherapy nausea, but also prevent nausea from occurring in the first place. Additionally, THC has been found to reduce conditioned rejection and chemotherapy-induced nausea.
This information has been adapted from Medical Marijuana Inc. and approved by our Chief Medical Officer.