Study: Topical CBD Treatment May Reduce Central Nervous System Inflammation

Photo Credit: Medical Jane

Photo Credit: Medical Jane

A recent controlled study published in Daru: Journal of Faculty and Pharmacy, Tehran University of Medical Sciences this year found topical treatments containing 1% purified CBD topical cream can reduce damage from brain inflammation. While the study was conducted on animals, it remains relevant to humans who suffer autoimmune diseases leading to demyelination, which occurs when the fatty covering around neurons are damaged. Such diseases include multiple sclerosis. 

The study used both healthy mice and mice given experimental autoimmune encephalomyelitis (EAE) as models for humans who suffer from MS. The mice then received either 1% purified CBD cream, inactive cream, or no cream and were observed daily for 28 days. The mice that received the CBD cream experienced reduced damage caused by EAE; they experienced a reversal in back leg paralysis (or their loss of muscle function), there were reduced indications of spinal cord damage like demyelination or white blood cell count, they released less lymphocytes in their spleen cells, and their inflammatory signals reduced.

This study further supports the use of CBD in the treatment of autoimmune and inflammatory diseases, while revealing the efficacy of topical treatment as a vehicle for administration. This information is brought to you by Medical Jane and approved by our Chief Medical Officer. Find the study abstract here.