Why Does Cannabis Affect Everyone Differently?

Photo Credit: Whaxy

Photo Credit: Whaxy

When it comes to treating your symptoms with medical marijuana, what works for you may not work for someone else. Part of this can be attributed to a person's tolerance and the strain's cannabinoid composition, but people may experience the same strain differently due to their own genetic makeup and psychological health. Considering the cannabinoid content of your strain is not a simple process. Scientists have recognized 85 different cannabinoids, and their ratios within in a strain along with the way the cannabinoids interact with each other can alter the effects of cannabis.

One study published in 2010 in the Journal of Neuropsychopharmacology looked at the combined effects of just THC and CBD, and found that CBD has the ability to block many of the negative effects associated with THC, like paranoia and anxiety. Therefore, high THC and low CBD strains are more likely to create a negative user experience. The study also pointed to how individual psychological differences can influence the way different strains impact different people. There is also a new research exploring the relationship between cannabis use and human genetics that recognizes additional influencers on an individual's experience with cannabis. Research has discovered a commonly occurring genetic variation can affect the impact THC has on working memory performance, so those who have the genetic variation experience cannabis differently than those who do not. 

This information has been brought to you by Whaxy and approved by our Chief Medical Officer.